A key player in driving cellular immunity, IFN-γ is capable of orchestrating numerous
protective functions to heighten immune responses in infections and cancers. It can exhibit …

Neddylation is one type of protein post‐translational modification by conjugating a ubiquitin‐
like protein neural precursor cell‐expressed developmentally downregulated protein 8 to …

The transcription-regulating activity of TFEB is dependent on its phosphorylation
modification, but the phosphatase (s) involved in TFEB dephosphorylation have remained …

Neddylation plays a vital role in post-translational modification, intricately shaping the
regulation of diverse biological processes, including those related to cellular immune …

Neddylation is a ubiquitin-like post-translational protein modification. It occurs via the
activation of the neural precursor cell expressed, developmentally downregulated protein 8 …

The cell wall of Mycobacterium tuberculosis is configured of bioactive lipid classes that are
essential for virulence and potentially involved in the formation of foamy macrophages (FMs) …

Post translational modifications (PTMs) are exploited by various pathogens in order to
escape host immune responses. SUMOylation is one of the PTMs which is involved in …

Background Toxoplasma gondii is an obligate intracellular parasite that can pose a serious
threat to human health by causing toxoplasmosis. There are no drugs that target the chronic …

Metformin (MET) is a potential combination drug to elevate anti-TB efficacy. However, the
clinical effect, especially smear reversion, during metformin applied with anti-tuberculosis …

The emergence of drug resistant strains of Mycobacterium tuberculosis (M. tuberculosis)
together with reports of co-infections with the human immunodeficiency virus (HIV) has …