2-Aryl-5-carboxytetrazole as a new photoaffinity label for drug target identification

A Herner, J Marjanovic, TM Lewandowski… - Journal of the …, 2016 - ACS Publications
Photoaffinity labels are powerful tools for dissecting ligand–protein interactions, and they
have a broad utility in medicinal chemistry and drug discovery. Traditional photoaffinity …

Sterically shielded, stabilized nitrile imine for rapid bioorthogonal protein labeling in live cells

P An, TM Lewandowski, TG Erbay… - Journal of the American …, 2018 - ACS Publications
In pursuit of fast bioorthogonal reactions, reactive moieties have been increasingly
employed for selective labeling of biomolecules in living systems, posing a challenge in …

The synthesis of iminothiophenone-fused quinolines and evaluation of their serendipitous reactions

M Shiri, Z Faghihi, HA Oskouei, MM Heravi… - RSC …, 2016 - pubs.rsc.org
The novel synthesis of tricyclic 2-(cyclohexylimino) thieno [2, 3-b] quinolin-3 (2H)-ones from
the reaction of 2-mercaptoquinoline-3-carbaldehydes and isocyanides in methanol without …

Metal-free C–C bond formation via coupling of nitrile imines and boronic acids

K Livingstone, S Bertrand, J Mowat, C Jamieson - Chemical Science, 2019 - pubs.rsc.org
The challenges of developing sustainable methods of carbon–carbon bond formation
remains a topic of considerable importance in synthetic chemistry. Capitalizing on the highly …

3-Mercaptopropionic acid–nitrile imine adducts. An unprecedented cyclization into 1, 3, 4-thiadiazol-2 (3 H)-ones and-2 (3 H)-thiones

JA Zahra, BAA Thaher, MM El-Abadelah… - Organic & Biomolecular …, 2005 - pubs.rsc.org
3-Mercaptopropionic acid–nitrile imine acyclic adducts (6a–c) undergo cyclocondensation
with 1, 1′-carbonyldiimidazole to afford the respective 1, 3, 4-thiadiazol-2-(3H)-ones (7a …

The Reactivity of Nitrile Imines

C Jamieson, K Livingstone, C Jamieson… - The Nitrile Imine 1, 3 …, 2020 - Springer
One of the most unique properties of nitrile imines in comparison to other 1, 3-dipoles is their
diverse reactivity profile with a number of distinct substrates. This chapter aims to categorise …

Using highly substituted isocyanides in the synthesis ofiminothiophenes fused to quinolines

M Shiri, S Fazelzadeh, Z Faghihi… - Applied Chemistry, 2018 - chemistry.semnan.ac.ir
In this manuscript the reaction of 2-mercaptoquinoline-3-carbaldehydes and 1, 1, 3, 3-
tetramethyl butylisocyanide as highly substituted isocyanide in the reflux of ethanol without …

استفاده از مشتقات ایزوسیانید پرشاخه‌ی زنجیری در سنتز ایمینو تیوفن‌های جوش خورده به حلقه‌های کینولینی

شیری, فاضل زاده, فقیهی, نوتاش - شیمى کاربردى روز, 2018‎ - chemistry.semnan.ac.ir
در این مقاله واکنش بین مشتقات مختلف 2-مرکاپتو‌کینولین-3-کربالدهید و ایزوسیانید پرشاخه‌ی
3، 3، 1، 1-تترامتیل بوتیل ایزوسیانید، با استفاده از حلال اتانول تحت شرایط رفلاکس و در …

N-arylaminomethylene benzothiophenones for treatment of cardiovascular disease

E Klussmann, W Rosenthal, J Milic… - US Patent …, 2015 - Google Patents
US9102667B2 - N-arylaminomethylene benzothiophenones for treatment of cardiovascular
disease - Google Patents US9102667B2 - N-arylaminomethylene benzothiophenones for …

[PDF][PDF] Jalal A. Zahra, Bassam A. Abu Thaher, b Mustafa M. El-Abadelah,* and

R Boese - HETEROCYCLES, 2004 - academia.edu
Abstract _ A synthesis of new 1, 3, 4-benzothiadiazepin-5-ones (6a-c) has been achieved
via cyclocondensation, promoted by acetic anhydride at reflux, of the corresponding acyclic …