Background Type 1 diabetes is a metabolic disorder resulting from a defect in insulin
secretion. Onset of type 1 diabetes mellitus may occur at any age and it is one of the most …

Background Clinical guidelines differ regarding their recommended blood glucose targets
for patients with type 1 diabetes and recent studies on patients with type 2 diabetes suggest …

To examine whether intensive glycemic control could decrease the frequency or severity of
diabetic microvascular complications, we performed a prospective study of Japanese …

Background A cause-and-effect relation between blood glucose concentrations and
microvascular complications in patients with insulin-dependent diabetes mellitus has not …

Aims We compared the effects of continuous subcutaneous insulin infusion (CSII) with those
of multiple daily insulin (MDI) injections on glycaemic control, risk of hypoglycaemic …

Tight blood glucose control has been speculated to reduce late complications in insulin-
dependent diabetics but results from individual studies have been inconsistent. We have …

Objective To revise and expand the 1992 edition of the clinical practice guidelines for the
management of diabetes in Canada incorporating recent advances in diagnosis and …

Diabetes mellitus is a chronic disease characterized by hyperglycemia and by complications
that include microvascular disease of the eye and kidney and a variety of clinical …

Effect of intensive therapy on the development and progression of diabetic nephropathy in
the Diabetes Control and Complications Trial. The Diabetes Control and Complications Trial …

For about 25 years, bromcresol green and bromcresol purple have been the basis for most
of the measurements of serum albumin in the US and perhaps in the world. The longevity of …