The expanding family of SMARCB1 (INI1)-deficient neoplasia: implications of phenotypic, biological, and molecular heterogeneity
A Agaimy - Advances in anatomic pathology, 2014 - journals.lww.com
Since the description of atypical teratoid/rhabdoid tumors of the central nervous system and
renal/extrarenal malignant rhabdoid tumors in children, the clinicopathologic spectrum of …
renal/extrarenal malignant rhabdoid tumors in children, the clinicopathologic spectrum of …
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner
J Han, J Wang, X Yang, H Yu, R Zhou, HC Lu… - Molecular cancer, 2019 - Springer
Background METTL3 is known to be involved in all stages in the life cycle of RNA. It affects
the tumor formation by the regulation the m6A modification in the mRNAs of critical …
the tumor formation by the regulation the m6A modification in the mRNAs of critical …
Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development
The identification of all epigenetic modifications (ie DNA methylation, histone modifications
and expression of noncoding RNAs such as microRNAs) involved in gene regulation is one …
and expression of noncoding RNAs such as microRNAs) involved in gene regulation is one …
miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ
Glioblastoma is the most frequent brain tumor in adults and is the most lethal form of human
cancer. Despite the improvements in treatments, survival of patients remains poor. In order …
cancer. Despite the improvements in treatments, survival of patients remains poor. In order …
In Vitro and In Vivo Activity of a Novel Locked Nucleic Acid (LNA)-Inhibitor-miR-221 against Multiple Myeloma Cells
MT Di Martino, A Gullà, ME Gallo Cantafio, E Altomare… - PloS one, 2014 - journals.plos.org
Background & Aim The miR-221/222 cluster is upregulated in malignant plasma cells from
multiple myeloma (MM) patients harboring the t (4; 14) translocation. We previously reported …
multiple myeloma (MM) patients harboring the t (4; 14) translocation. We previously reported …
RETRACTED: Overexpression of miR-222-3p Promotes the Proliferation and Inhibits the Apoptosis of Diffuse Large B-Cell Lymphoma Cells via Suppressing …
S Sun, H Wang, M Ji - Technology in cancer research & …, 2019 - journals.sagepub.com
Purpose: This study aimed to investigate the effects of microRNA-222-3p on activated B cell-
like-type diffuse large B-cell lymphoma cells and the regulatory relationship between …
like-type diffuse large B-cell lymphoma cells and the regulatory relationship between …
MicroRNA and pediatric tumors: Future perspectives
A better understanding of pediatric tumor biology is needed to allow the development of less
toxic and more efficient therapies, as well as to provide novel reliable biomarkers for …
toxic and more efficient therapies, as well as to provide novel reliable biomarkers for …
MiR-221/222 promote migration and invasion, and inhibit autophagy and apoptosis by modulating ATG10 in aggressive papillary thyroid carcinoma
H Shen, Z Lin, H Shi, L Wu, B Ma, H Li, B Yin, J Tang… - 3 Biotech, 2020 - Springer
MicroRNA (miRNA) has been reported to exert important functions in papillary thyroid
carcinomas (PTC). However, the role of miRNA in aggressive PTC (APTC) remains unclear …
carcinomas (PTC). However, the role of miRNA in aggressive PTC (APTC) remains unclear …
MicroRNA signatures as biomarkers and therapeutic target for CNS embryonal tumors: the pros and the cons
T Shalaby, G Fiaschetti, M Baumgartner… - International journal of …, 2014 - mdpi.com
Embryonal tumors of the central nervous system represent a heterogeneous group of
childhood cancers with an unknown pathogenesis; diagnosis, on the basis of histological …
childhood cancers with an unknown pathogenesis; diagnosis, on the basis of histological …
MicroRNA142-3p promotes tumor-initiating and radioresistant properties in malignant pediatric brain tumors
YY Lee, YP Yang, MC Huang, ML Wang… - Cell …, 2014 - journals.sagepub.com
Primary central nervous system (CNS) atypical teratoid/rhabdoid tumor (ATRT) is an
extremely malignant pediatric brain tumor observed in infancy and childhood. It has been …
extremely malignant pediatric brain tumor observed in infancy and childhood. It has been …