[HTML][HTML] ChatGPT and the rise of generative AI: Threat to academic integrity?

DO Eke - Journal of Responsible Technology, 2023 - Elsevier
The emergence of OpenAI's ChatGPT has put intense spotlight on Generative AI (Gen-AI)
systems and their possible impacts on Academic integrity. This paper provides an overview …

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases

S Harguindey, D Stanciu, J Devesa, K Alfarouk… - Seminars in cancer …, 2017 - Elsevier
During the last few years, the understanding of the dysregulated hydrogen ion dynamics and
reversed proton gradient of cancer cells has resulted in a new and integral pH-centric …

Cancer: fundamentals behind pH targeting and the double-edged approach

T Koltai - OncoTargets and therapy, 2016 - Taylor & Francis
The highly regulated pH of cells and the less-regulated pH of the surrounding extracellular
matrix (ECM) is the result of a delicate balance between metabolic processes and proton …

iNOS regulates the therapeutic response of pancreatic cancer cells to radiotherapy

PMR Pereira, KJ Edwards, K Mandleywala, LM Carter… - Cancer research, 2020 - AACR
Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to radiotherapy,
chemotherapy, or a combination of these modalities, and surgery remains the only curative …

Neutrophil extracellular trap formation correlates with favorable overall survival in high grade ovarian cancer

B Muqaku, D Pils, JC Mader, S Aust, A Mangold… - Cancers, 2020 - mdpi.com
It is still a question of debate whether neutrophils, often found in the tumor
microenvironment, mediate tumor-promoting or rather tumor-inhibiting activities. The present …

Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus

J Araos, L Silva, R Salsoso, T Sáez, E Barros, F Toledo… - Placenta, 2016 - Elsevier
The placenta is a vital organ whose function in diseases of pregnancy is altered, resulting in
an abnormal supply of nutrients to the foetus. The lack of placental vasculature homeostasis …

[HTML][HTML] Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer

C Sanhueza, J Araos, L Naranjo, F Toledo… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Cancer cells generate protons (H+) that are extruded to the extracellular medium mainly via
the Na+/H+ exchanger 1 (NHE1), which regulates intracellular pH (pHi) and cell …

Caveolin-1-mediated tumor suppression is linked to reduced HIF1α S-Nitrosylation and transcriptional activity in hypoxia

C Sanhueza, JC Bennett, M Valenzuela-Valderrama… - Cancers, 2020 - mdpi.com
Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a
tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin …

High SLC4A11 expression is an independent predictor for poor overall survival in grade 3/4 serous ovarian cancer

L Qin, T Li, Y Liu - PLoS One, 2017 - journals.plos.org
In this study, we aimed to examine the expression of SLC4A11 in ovarian cancer and in
normal ovarian tissues, its prognostic value and the possible mechanism of its …

Potential Coagulation Factor-Driven Pro-Inflammatory Responses in Ovarian Cancer Tissues Associated with Insufficient O2 and Plasma Supply

S Koizume, Y Miyagi - International Journal of Molecular Sciences, 2017 - mdpi.com
Tissue factor (TF) is a cell surface receptor for coagulation factor VII (fVII). The TF-activated
fVII (fVIIa) complex is an essential initiator of the extrinsic blood coagulation process …