The LC3 interactome at a glance
Continuous synthesis of all cellular components requires their constant turnover in order for
a cell to achieve homeostasis. To this end, eukaryotic cells are endowed with two …
a cell to achieve homeostasis. To this end, eukaryotic cells are endowed with two …
Choose your partners: dimerization in eukaryotic transcription factors
In many eukaryotic transcription factor gene families, proteins require a physical interaction
with an identical molecule or with another molecule within the same family to form a …
with an identical molecule or with another molecule within the same family to form a …
[HTML][HTML] Chemical proteomics identifies druggable vulnerabilities in a genetically defined cancer
The transcription factor NRF2 is a master regulator of the cellular antioxidant response, and
it is often genetically activated in non-small-cell lung cancers (NSCLCs) by, for instance …
it is often genetically activated in non-small-cell lung cancers (NSCLCs) by, for instance …
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors
S Pfefferle, J Schöpf, M Kögl, CC Friedel… - PLoS …, 2011 - journals.plos.org
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal
respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute …
respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute …
HIPPIE: Integrating protein interaction networks with experiment based quality scores
Protein function is often modulated by protein-protein interactions (PPIs) and therefore
defining the partners of a protein helps to understand its activity. PPIs can be detected …
defining the partners of a protein helps to understand its activity. PPIs can be detected …
Hepatitis C virus infection protein network
B De Chassey, V Navratil, L Tafforeau… - Molecular systems …, 2008 - embopress.org
A proteome‐wide mapping of interactions between hepatitis C virus (HCV) and human
proteins was performed to provide a comprehensive view of the cellular infection. A total of …
proteins was performed to provide a comprehensive view of the cellular infection. A total of …
Diversity in Genetic In Vivo Methods for Protein-Protein Interaction Studies: from the Yeast Two-Hybrid System to the Mammalian Split-Luciferase System
B Stynen, H Tournu, J Tavernier… - … and molecular biology …, 2012 - Am Soc Microbiol
The yeast two-hybrid system pioneered the field of in vivo protein-protein interaction
methods and undisputedly gave rise to a palette of ingenious techniques that are constantly …
methods and undisputedly gave rise to a palette of ingenious techniques that are constantly …
Recent advances in predicting protein–protein interactions with the aid of artificial intelligence algorithms
Protein–protein interactions (PPIs) are essential in the regulation of biological functions and
cell events, therefore understanding PPIs have become a key issue to understanding the …
cell events, therefore understanding PPIs have become a key issue to understanding the …
PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome
I Ebermann, JB Phillips, MC Liebau… - The Journal of …, 2010 - Am Soc Clin Investig
Usher syndrome is a genetically heterogeneous recessive disease characterized by hearing
loss and retinitis pigmentosa (RP). It frequently presents with unexplained, often intrafamilial …
loss and retinitis pigmentosa (RP). It frequently presents with unexplained, often intrafamilial …
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity
A Kempf, B Tews, ME Arzt, O Weinmann… - PLoS …, 2014 - journals.plos.org
Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite
growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20 …
growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20 …