The human ether-à-go-go related gene (HERG) encodes the alpha subunit of Kv11. 1, which
is a voltage-gated K+ channel protein mainly expressed in heart and brain tissue. HERG …

What is known and objective In order to expedite the availability of drugs to treat cancers in a
cost‐effective manner, repurposing of old drugs for oncological indications is gathering …

KCNH2 encodes the human ether-a-go-go-related gene (hERG) potassium channel and is
an important repolarization reserve for regulating cardiac electrical activity. Increasing …

Background/Aim: hERG potassium channels enhance tumor invasiveness and breast
cancer proliferation. MicroRNA (miRNA) dysregulation during cancer controls gene …

Modern molecular imaging techniques have greatly improved tumor detection and post-
treatment follow-up of cancer patients. In this context, antibody-based imaging is rapidly …

Neoplastic transformation is reportedly associated with alterations of the potassium transport
across plasma and intracellular membranes. These alterations have been identified as …

Notable advances in treatment have been made and increases in the cure rates of pediatric
leukemia have been achieved. However, the majority of children with relapsed disease are …

Head and neck cancers are a highly complex and heterogeneous group of malignancies
that involve very diverse anatomical structures and distinct aetiological factors, treatments …

Many tumor cells express highly elevated activities of voltage-gated K+ channels in the
plasma membrane which are indispensable for tumor growth. To test for K+ channel function …

Macrolide antibiotics (MAs) have a wide spectrum of activities against Gram-positive
bacteria, but they have also been proposed as anticancer drugs for multiple tumor types. 1 …