Taxanes are a key chemotherapy component for several malignancies, including metastatic
breast cancer (MBC), ovarian cancer, and advanced non-small cell lung cancer (NSCLC) …

Although human papillomavirus (HPV) infection has been found in most of the cervical
cancer cases, additional genetic and epigenetic changes are required for disease …

Dysregulated mitochondrial function is a hallmark of immune-mediated inflammatory
diseases. Cytochrome c oxidase (C c O), which mediates the rate-limiting step in …

Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses
infecting human epithelial cells, are associated with various benign and malignant lesions of …

OBJECTIVE: We wanted to identify the most promising methylation marker candidates for
cervical cancer early detection. METHODS: A systematic literature review was performed in …

Tumor growth is essentially the result of an evolving cross-talk between malignant and
surrounding stromal cells (fibroblasts, endothelial cells and inflammatory cells). This …

The ability to effectively target a tumor to achieve complete regression and cure is the
ultimate goal that drives our need to better understand tumor biology. Recently, SPARC has …

We have used a gene expression array–based strategy to identify the methylation of tissue
factor pathway inhibitor 2 (TFPI2), a potential tumor suppressor gene, as a frequent event in …

Cervical cancer arises from cells localized in the ectoendocervical squamocolumnar
junction of the cervix persistently infected with one of about 13 human papillomavirus (HPV) …

While organized screening programs in industrialized countries have significantly reduced
cervical cancer incidence, cytology-based screening has several limitations. Equivocal or …