CTLA-4 and PD-1 control of T-cell motility and migration: implications for tumor immunotherapy
MC Brunner-Weinzierl, CE Rudd - Frontiers in immunology, 2018 - frontiersin.org
CTLA-4 is a co-receptor on T-cells that controls peripheral tolerance and the development of
autoimmunity. Immune check-point blockade (ICB) uses monoclonal antibodies (MAbs) to …
autoimmunity. Immune check-point blockade (ICB) uses monoclonal antibodies (MAbs) to …
The emerging role of regulatory cell-based therapy in autoimmune disease
F Ghobadinezhad, N Ebrahimi, F Mozaffari… - Frontiers in …, 2022 - frontiersin.org
Autoimmune disease, caused by unwanted immune responses to self-antigens, affects
millions of people each year and poses a great social and economic burden to individuals …
millions of people each year and poses a great social and economic burden to individuals …
International consensus for the treatment of autoimmune pancreatitis
Abstract Background and aims The International Consensus Diagnostic Criteria (ICDC) for
AIP has proposed two distinctive type of AIP, type 1 and type 2, and enabled us first to …
AIP has proposed two distinctive type of AIP, type 1 and type 2, and enabled us first to …
Recent advances in autoimmune pancreatitis
Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis that is characterized clinically
by frequent presentation with obstructive jaundice, histologically by a dense …
by frequent presentation with obstructive jaundice, histologically by a dense …
Mechanism of cyclosporine A nephrotoxicity: Oxidative stress, autophagy, and signalings
Q Wu, X Wang, E Nepovimova, Y Wang, H Yang… - Food and chemical …, 2018 - Elsevier
Cyclosporine A (CsA) is a widely used immunosuppressive agent that greatly reduces the
rates of kidney-, heart-, and liver-transplant rejection. However, CsA nephrotoxicity is a …
rates of kidney-, heart-, and liver-transplant rejection. However, CsA nephrotoxicity is a …
Republished: recent advances in autoimmune pancreatitis: type 1 and type 2
Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis characterised clinically by
frequent presentation with obstructive jaundice, histologically by a lymphoplasmacytic …
frequent presentation with obstructive jaundice, histologically by a lymphoplasmacytic …
[HTML][HTML] Complement component 5 mediates development of fibrosis, via activation of stellate cells, in 2 mouse models of chronic pancreatitis
Background & Aims Little is known about the pathogenic mechanisms of chronic
pancreatitis. We investigated the roles of complement component 5 (C5) in pancreatic …
pancreatitis. We investigated the roles of complement component 5 (C5) in pancreatic …
Engineered antigen-specific regulatory T cells for autoimmune skin conditions
Regulatory T cells (Tregs) are a subset of T cells responsible for the regulation of immune
responses, thereby maintaining immune homeostasis and providing immune tolerance to …
responses, thereby maintaining immune homeostasis and providing immune tolerance to …
Regulatory T cell heterogeneity and therapy in autoimmune diseases
R Zhang, J Miao, P Zhu - Autoimmunity reviews, 2021 - Elsevier
Regulatory T (Treg) cells are a group of CD4+ T cell with high expression of CD25 and cell
linage specific transcription factor forkhead box P3 (Foxp3) and play a vital role in …
linage specific transcription factor forkhead box P3 (Foxp3) and play a vital role in …
Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis
Acute pancreatitis is a complex disorder involving both premature intracellular protease
activation and inflammatory cell invasion. An initiating event is the intracellular activation of …
activation and inflammatory cell invasion. An initiating event is the intracellular activation of …