The need for clean air: the way air pollution and climate change affect allergic rhinitis and asthma

I Eguiluz‐Gracia, AG Mathioudakis, S Bartel… - Allergy, 2020 - Wiley Online Library
Air pollution and climate change have a significant impact on human health and well‐being
and contribute to the onset and aggravation of allergic rhinitis and asthma among other …

Autoimmune pre-disease

K Bieber, JE Hundt, X Yu, M Ehlers, F Petersen… - Autoimmunity …, 2023 - Elsevier
Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …

[HTML][HTML] VCAM-1 as a predictor biomarker in cardiovascular disease

MF Troncoso, J Ortiz-Quintero… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The vascular cellular adhesion molecule-1 (VCAM-1) is a protein that canonically
participates in the adhesion and transmigration of leukocytes to the interstitium during …

The health effects of traffic-related air pollution: A review focused the health effects of going green

X Bai, H Chen, BG Oliver - Chemosphere, 2022 - Elsevier
Traffic-related air pollution (TRAP) is global concern due to both the ecological damage of
TRAP and the adverse health effects in Humans. Several strategies to reduce TRAP have …

[HTML][HTML] Toxicity and health effects of ultrafine particles: Towards an understanding of the relative impacts of different transport modes

NVS Vallabani, O Gruzieva, K Elihn… - Environmental …, 2023 - Elsevier
Exposure to particulate matter (PM) has been associated with a wide range of adverse
health effects, but it is still unclear how particles from various transport modes differ in terms …

[HTML][HTML] Phosphodiesterases as therapeutic targets for respiratory diseases

H Zuo, I Cattani-Cavalieri, N Musheshe… - Pharmacology & …, 2019 - Elsevier
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and
asthma, affect millions of people all over the world. Cyclic adenosine monophosphate …

PM2. 5 induced pulmonary fibrosis in vivo and in vitro

Z Xu, Z Li, Z Liao, S Gao, L Hua, X Ye, Y Wang… - Ecotoxicology and …, 2019 - Elsevier
Epidemiological studies have revealed positive correlation between particulate matter with
an aerodynamic diameter of< 2.5 µm (PM 2.5) and pulmonary fibrosis (PF). As etiology and …

What makes antibodies against G protein-coupled receptors so special? A novel concept to understand chronic diseases

G Riemekasten, F Petersen, H Heidecke - Frontiers in Immunology, 2020 - frontiersin.org
Expressions of G protein-coupled receptors (GPCR) on immune and tissue resident cells are
the consequence of the cellular environment, which is highly variable. As discussed here …

Nrf2 positively regulates autophagy antioxidant response in human bronchial epithelial cells exposed to diesel exhaust particles

DP Frias, RLN Gomes, K Yoshizaki… - Scientific Reports, 2020 - nature.com
Diesel exhaust particles (DEP) are known to generate reactive oxygen species in the
respiratory system, triggering cells to activate antioxidant defence mechanisms, such as …

Air pollution effects in allergies and asthma

A Nanda, SS Mustafa, M Castillo… - … and Allergy Clinics, 2022 - immunology.theclinics.com
Outdoor air pollution is associated with exacerbations of allergic diseases, including asthma,
allergic rhinitis (AR), and other atopic conditions. 1 Both new onset of these conditions and …