After ascent to high altitude (≥ 2500 m), the inability of the human body to adapt to the
hypobaric and hypoxia environment can induce tissue hypoxia, then a series of high altitude …

Background High altitude illness (HAI) is a term used to describe a group of cerebral and
pulmonary syndromes that can occur during travel to elevations above 2500 metres (8200 …

Pharmacotherapy in acute mountain sickness (AMS) for the past half century has largely
rested on the use of carbonic anhydrase (CA) inhibitors, such as acetazolamide, and …

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), triggered by various
pathogenic factors inside and outside the lungs, leads to diffuse lung injury and can result in …

Background Inhaled budesonide has been suggested as a novel prevention for acute
mountain sickness. However, efficacy has not been compared with the standard acute …

Background Chronic obstructive pulmonary disease (COPD) may predispose to
symptomatic pulmonary hypertension at high altitude. We investigated hemodynamic …

The current pandemic of surgical complications necessitates urgent and pragmatic
innovation to reduce postoperative morbidity and mortality, which are associated with poor …

In order to investigate the pharmacokinetics of a combination of diazepam and
dexamethasone under hypoxic conditions, a novel, sensitive and specific liquid …

Background High altitude illness (HAI) is a term used to describe a group of mainly cerebral
and pulmonary syndromes that can occur during travel to elevations above 2500 metres (˜ …

In older individuals, pulmonary artery pressure rises markedly during exercise, probably due
in part to increased pulmonary vascular resistance and in part to an increase in left‐heart …