Flavonoids and genomic instability induced by ionizing radiation

SJ Hosseinimehr - Drug discovery today, 2010 - Elsevier
DNA is the cellular target that has the most damage induced by ionizing radiation (IR). If
genomic instability resulting from this DNA damage is not correctly repaired, it leads to …

Effects of Gentiana lutea root on vascular diseases

G Joksic, D Radak, E Sudar-Milovanovic… - Current Vascular …, 2021 - ingentaconnect.com
Background: Gentiana lutea (GL), commonly known as yellow gentian, bitter root, and
bitterwort, belongs to family Gentianaceae. GL belongs to genus Gentiana, which is a rich …

Inhibition of Vascular Smooth Muscle Cell Proliferation by Gentiana lutea Root Extracts

R Kesavan, UR Potunuru, B Nastasijević, G Joksić… - PLoS …, 2013 - journals.plos.org
Gentiana lutea belonging to the Gentianaceae family of flowering plants are routinely used
in traditional Serbian medicine for their beneficial gastro-intestinal and anti-inflammatory …

Apigenin ameliorates gamma radiation-induced cytogenetic alterations in cultured human blood lymphocytes

N Begum, NR Prasad, G Kanimozhi… - Mutation Research/Genetic …, 2012 - Elsevier
The aim of the present study was to assess the protective effect of apigenin, a dietary
flavone, against cytogenetic alterations in human peripheral blood lymphocytes (HPBL) …

The Use of 3,5,4′-Tri-O-acetylresveratrol as a Potential Prodrug for Resveratrol Protects Mice from γ-Irradiation-Induced Death

K Koide, S Osman, AL Garner, F Song… - ACS medicinal …, 2011 - ACS Publications
Currently, no drugs are available to protect humans from γ-irradiation-induced death.
Because reactive oxygen species are produced upon exposure to γ-irradiation and directly …

Gentiopicroside and swertiamarin induce non-selective oxidative stress-mediated cytotoxic effects in human peripheral blood mononuclear cells

AV Šobot, D Drakulić, A Todorović, M Janić… - Chemico-Biological …, 2024 - Elsevier
Abstract Gentiopicroside (Gp) and swertiamarin (Sm), secoiridoid glycosides commonly
found in plants of the Gentianaceae family, differ in one functional group. They exhibit …

Bioactive secondary metabolites in several genera of Gentianaceae species from the central regions of the Balkan Peninsula

K Šavikin, IS Aljančić, VE Vajs, SM Milosavljević… - … Gentianaceae-Volume 2 …, 2015 - Springer
The results are presented of phytochemical investigations, during the last decade, of some
wild-growing species of the family Gentianaceae from Serbia and Montenegro. Some of the …

Potential of Gentiana lutea for the Treatment of Obesity-associated Diseases

G Joksić, JF Tričković, I Joksić - Current pharmaceutical design, 2019 - ingentaconnect.com
Background: Obesity, diabetes, and associated diseases are increasing all over the world,
and pose a great burden on public health. According to the latest reports, 440 million people …

Biotechnology and Phytochemistry of Gentianella Species from the Central Regions of the Balkan Peninsula

D Krstić-Milošević, B Vinterhalter, T Janković… - … Gentianaceae-Volume 2 …, 2015 - Springer
In the central regions of the Balkan Peninsula, the genus Gentianella is represented by six
species. Five of them G. albanica, G. austriaca, G. bulgarica, G. ciliata, and G. crispata were …

Genus Gentianella Moench: A phytochemical and ethnopharmacological review

M LI, LI Li, Y Yang, N Zhang, X Song… - Chinese Herbal …, 2010 - pesquisa.bvsalud.org
The plants in genus Gentianella Moench (Gentianaceae) which comprised approximately
250 species, are mainly distributed in temperate regions of the world. Many Gentianella …