In contrast to the multiple disease-modifying therapies that are available for relapsing–
remitting multiple sclerosis (MS), the therapeutic options for progressive MS (PMS) are …

There are over 15 disease-modifying drugs that have been approved over the last 20 years
for the treatment of relapsing–remitting multiple sclerosis (MS), but there are limited …

Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

This article provides recommendations for implementing QSM for clinical brain research. It is
a consensus of the International Society of Magnetic Resonance in Medicine, Electro …

A key aim in epidemiological neuroscience is identification of markers to assess brain health
and monitor therapeutic interventions. Quantitative susceptibility mapping (QSM) is an …

Although multiple sclerosis has traditionally been considered a white matter disease,
extensive research documents the presence and importance of grey matter injury including …

Quantitative susceptibility mapping (QSM) has gained broad interest in the field by extracting
bulk tissue magnetic susceptibility, predominantly determined by myelin, iron and calcium …

Iron is an essential element involved in a multitude of bodily processes. It is tightly regulated,
as elevated deposition in tissues is associated with diseases such as multiple sclerosis …

Background Gray matter (GM) pathology is closely associated with physical and cognitive
impairment in persons with multiple sclerosis (PwMS). Similarly, serum neurofilament light …

Multiple Sclerosis (MS) is an autoimmune demyelinating disease characterised by changes
in iron and myelin content. These biomarkers are detectable by Quantitative Susceptibility …