Metastasis represents one of the most dangerous issue of cancer progression, characterized
by intricate interactions between invading tumor cells, various proteins, and other cells on …

Epithelial–mesenchymal transition (EMT) causes epithelial cells to lose their polarity and
adhesion property, and endows them with migratory and invasive properties to enable them …

Cancer is one of the most important health problems and the second leading cause of death
worldwide. Despite the advances in oncology, cancer heterogeneity remains challenging to …

With increases in the mortality rate and number of patients with prostate cancer (PCa), PCa,
particularly the advanced and metastatic disease, has been the focus of a number of studies …

Enzalutamide (Enz) is a next-generation androgen receptor (AR) antagonist used to treat
castration-resistant prostate cancer (CRPC). Unfortunately, the relapsing nature of CRPC …

Exosomes are multivesicular bodies of which the plasma membrane fuse to release the
caring moiety into the surrounding body fluids. They are best known for their function in …

Prostate cancer (PC) is a very important kind of male malignancies. When PC evolves into a
stage of hormone resistance or metastasis, the fatality rate is very high. Currently …

Our understanding of cancer and the key pathways that drive cancer survival has expanded
rapidly over the past several decades. However, there are still important challenges that …

Therapy-induced neuroendocrine prostate cancer (NEPC), an extremely aggressive variant
of castration-resistant prostate cancer (CRPC), is increasing in incidence with the …

Purpose To investigate the protective effects of miR-301 in exosomes secreted by bone
mesenchymal stem cells (BMSCs) on rats' myocardial infarction (MI). Methods After isolation …