Serotonin and brain function: a tale of two receptors

RL Carhart-Harris, DJ Nutt - Journal of psychopharmacology, 2017 - journals.sagepub.com
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors

MV Vargas, LE Dunlap, C Dong, SJ Carter, RJ Tombari… - Science, 2023 - science.org
Decreased dendritic spine density in the cortex is a hallmark of several neuropsychiatric
diseases, and the ability to promote cortical neuron growth has been hypothesized to …

Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

S Ross, A Bossis, J Guss… - Journal of …, 2016 - journals.sagepub.com
Background: Clinically significant anxiety and depression are common in patients with
cancer, and are associated with poor psychiatric and medical outcomes. Historical and …

The paradoxical psychological effects of lysergic acid diethylamide (LSD)

RL Carhart-Harris, M Kaelen, M Bolstridge… - Psychological …, 2016 - cambridge.org
BackgroundLysergic acid diethylamide (LSD) is a potent serotonergic hallucinogen or
psychedelic that modulates consciousness in a marked and novel way. This study sought to …

Molecular mechanisms of psilocybin and implications for the treatment of depression

S Ling, F Ceban, LMW Lui, Y Lee, KM Teopiz… - CNS drugs, 2022 - Springer
Therapeutic deficiencies with monoaminergic antidepressants invites the need to identify
and develop novel rapid-acting antidepressants. Hitherto, ketamine and esketamine are …

[图书][B] Incognito

D Eagleman - 2022 - books.google.com
Numa experiência recente, foi pedido a um grupo de homens que classificasse várias
fotografias de mulheres segundo o grau de atração. Metade delas tinha os olhos dilatados …

Recent advances in the neuropsychopharmacology of serotonergic hallucinogens

AL Halberstadt - Behavioural brain research, 2015 - Elsevier
Abstract Serotonergic hallucinogens, such as (+)-lysergic acid diethylamide, psilocybin, and
mescaline, are somewhat enigmatic substances. Although these drugs are derived from …

Major depressive disorder

RH Belmaker, G Agam - New England Journal of Medicine, 2008 - Mass Medical Soc
This review of major depressive disorder is a comprehensive account of the genetic,
biochemical, and neurophysiological changes that have been implicated in the disorder. No …

The neurobiology of psychedelic drugs: implications for the treatment of mood disorders

FX Vollenweider, M Kometer - Nature Reviews Neuroscience, 2010 - nature.com
After a pause of nearly 40 years in research into the effects of psychedelic drugs, recent
advances in our understanding of the neurobiology of psychedelics, such as lysergic acid …

New insights into symptoms and neurocircuit function of anorexia nervosa

WH Kaye, JL Fudge, M Paulus - Nature Reviews Neuroscience, 2009 - nature.com
Individuals with anorexia nervosa have a relentless preoccupation with dieting and weight
loss that results in severe emaciation and sometimes death. It is controversial whether such …