AC Dolphin - The Journal of physiology, 2016 - Wiley Online Library
Voltage‐gated calcium channels are essential players in many physiological processes in excitable cells. There are three main subdivisions of calcium channel, defined by the pore …
Voltage-gated calcium (Ca 2+) channels initiate release of neurotransmitters at synapses, and regulation of presynaptic Ca 2+ channels has a powerful influence on synaptic strength …
S Heyes, WS Pratt, E Rees, S Dahimene, L Ferron… - Progress in …, 2015 - Elsevier
This review summarises genetic studies in which calcium channel genes have been connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and …
H Cheng, WJ Lederer - Physiological reviews, 2008 - journals.physiology.org
The calcium ion (Ca2+) is the simplest and most versatile intracellular messenger known. The discovery of Ca2+ sparks and a related family of elementary Ca2+ signaling events has …
M Ben-Johny, DT Yue - Journal of General Physiology, 2014 - rupress.org
Calmodulin regulation (calmodulation) of the family of voltage-gated CaV1-2 channels comprises a prominent prototype for ion channel regulation, remarkable for its powerful …
This review addresses the localized regulation of voltage-gated ion channels by phosphorylation. Comprehensive data on channel regulation by associated protein kinases …
AB Parekh - Trends in biochemical sciences, 2011 - cell.com
A rise in cytosolic Ca 2+ concentration is used as a universal signalling mechanism to control biological processes as diverse as exocytosis, contraction, cell growth and cell …
Recent work has identified missense mutations in calmodulin (CaM) that are associated with severe early-onset long-QT syndrome (LQTS), leading to the proposition that altered CaM …
T Pangrsic, JH Singer, A Koschak - Physiological reviews, 2018 - journals.physiology.org
Calcium influx through voltage-gated Ca (CaV) channels is the first step in synaptic transmission. This review concerns CaV channels at ribbon synapses in primary sense …