Physical exercise (PE) improves physical performance, mental status, general health, and
well-being. It does so by affecting many mechanisms at the cellular and molecular level. PE …

Stressful experiences, both physical and psychological, that are overwhelming (ie,
inescapable and unpredictable), can measurably affect subsequent neuronal properties and …

Alzheimer's disease (AD) is the most common cause of dementia and there is currently no
cure. Novel approaches to treat AD and curb the rapidly increasing worldwide prevalence …

One of the major obstacles that prevents an effective therapeutic intervention against
ischemic stroke is the lack of neuroprotective agents able to reduce neuronal damage; this …

The accumulated evidence from animal and human studies supports that exercise is
beneficial to physical health. Exercise can upregulate various neurotrophic factors, activate …

Exercise is one of the most effective treatments for the diseases of aging. In recent years, a
growing number of researchers have used Drosophila melanogaster to study the broad …

Understanding how physical exercise (PE) can influence brain function, especially
cognition, through the modulatory effects of brain-derived neurotrophic factor (BDNF) has …

Physical exercise is a powerful modulator of learning and memory. Mechanisms underlying
the cognitive benefits of exercise are well documented in adult rodents. Exercise studies …

Clinical studies show that physical exercise has anxiolytic and pro-cognitive properties for
both healthy individuals and psychiatric patients. Most of these data refer to the effects of …

Physical exercise during adolescence, a critical developmental window, can facilitate
neurogenesis in the dentate gyrus and astrogliogenesis in Cornu Ammonis (CA) …