The Huisgen 1, 3-dipolar cycloaddition reaction of organic azides and alkynes1, 2 has
gained considerable attention in recent years due to the introduction in 2001 of Cu (1) …

In recent years, there has been an ever‐increasing need for rapid reactions that meet the
three main criteria of an ideal synthesis: efficiency, versatility, and selectivity. Such reactions …

In most general terms, polymers and their supramolecular assemblies have been defining
life on this planet since its conception. Polymers of nucleic acids carry the code of life and …

The concept of “click” chemistry, introduced by Sharpless and coworkers a couple of years
ago, promotes the use of efficient, selective and versatile chemical reactions in synthetic …

This critical review concerns the impact of copper-mediated alkyne–azide cycloadditions on
peptidomimetic studies. It discusses how this reaction has been used to insert triazoles into …

The CuAAC “click” reaction has developed as one of the most useful and widely employed
reactions in ligation within polymer chemistry. This is due to the unique properties of the Cu …

This tutorial review examines recent developments involving use of Copper-catalyzed Azide-
Alkyne [3+ 2] Cycloaddition (CuAAC) reactions in the synthesis, modification, and …

Oligomers of N-substituted glycine, or peptoids, are versatile tools to probe biological
processes and hold promise as therapeutic agents. An underlying theme in the majority of …

CuI-catalyzed azide− alkyne cycloadditions were conducted in organic media under various
conditions. The effects of several parameters (ligand, solvent, reducing agent, metal) on …

Foldamers are an intriguing family of biomimetic oligomers that exhibit a propensity to adopt
stable secondary structures. N-Substituted glycine oligomers, or “peptoids”, are a …