The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

The maternal polyinosinic: polycytidylic acid (poly (I: C)) animal model is frequently used to
study how maternal immune activation may impact neuro development in the offspring …

Background In previous work, we applied novel in vivo imaging methods to reveal that white
matter pathology in patients with first-episode psychosis (FEP) is mainly characterized by …

Abstract Background and Hypothesis Low-grade neural and peripheral inflammation are
among the proposed pathophysiological mechanisms of schizophrenia. White matter …

Maternal inflammation during pregnancy causes later-in-life alterations of the offspring's
brain structure and function. These abnormalities increase the risk of developing several …

Schizophrenia is considered a neurodevelopmental disorder as it often manifests before full
brain maturation and is also a cerebral cortical disorder where deficits in GABAergic …

The maternal system's exposure to pathogens influences foetal brain development through
the influx of maternal cytokines and activation of the foetal immune status to a persistent …

Alterations in GABAergic interneurons and glutamic acid decarboxylase (GAD) are observed
in the brains of people with schizophrenia. Studies also show increased density of interstitial …