Bees—including solitary, social, wild, and managed species—are key pollinators of
flowering plant species, including nearly three-quarters of global food crops. Their …

The sarcomere is the basic contractile unit of striated muscle and is a highly ordered protein
complex with the actin and myosin filaments at its core. Assembling the sarcomere …

All species need to reproduce to maintain viable populations, but heat stress kills sperm
cells across the animal kingdom and rising frequencies of heat waves are a threat to …

The objective of this study was to determine the proteolytic changes of myofibrillar and small
heat shock proteins (HSPs) in different muscles during aging and to evaluate their relevance …

Background Human pluripotent stem cells (hPSCs) provide powerful models for studying
cellular differentiations and unlimited sources of cells for regenerative medicine. However, a …

Skeletal muscle and the nervous system depend on efficient protein quality control, and they
express chaperones and cochaperones at high levels to maintain protein homeostasis …

Hepatic ischemia/reperfusion injury (IRI) is an unavoidable course in liver transplantation,
during which the immune response of inflammation plays a leading part. MicroRNA-450b-5p …

The dilemma of how to categorize and classify diseases has been debated for centuries.
The field of medical genetics has historically approached nosology based on clinical …

Myofibrillar myopathy (MFM) is a group of inherited muscular disorders characterized by
myofibril dissolution and abnormal accumulation of degradation products. The diagnosis of …

Elevated temperature can have detrimental effects on the physiological performance of
many marine organisms. However, phenotypic plasticity may enable some populations to …