Herpesvirus latency

JI Cohen - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
Herpesviruses infect virtually all humans and establish lifelong latency and reactivate to
infect other humans. Latency requires multiple functions: maintaining the herpesvirus …

The interplay between viral-derived miRNAs and host immunity during infection

R Mishra, A Kumar, H Ingle, H Kumar - Frontiers in immunology, 2020 - frontiersin.org
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene
expression during cellular processes. The host-encoded miRNAs are known to modulate the …

Viruses, microRNAs, and host interactions

RL Skalsky, BR Cullen - Annual review of microbiology, 2010 - annualreviews.org
One of the most significant recent advances in biomedical research has been the discovery
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …

[HTML][HTML] Virus-encoded microRNAs

A Grundhoff, CS Sullivan - Virology, 2011 - Elsevier
MicroRNAs (miRNAs) are the subject of enormous interest. They are small non-coding
RNAs that play a regulatory role in numerous and diverse cellular processes such as …

MicroRNA involvement in signaling pathways during viral infection

MG Barbu, CE Condrat, DC Thompson… - Frontiers in cell and …, 2020 - frontiersin.org
The study of miRNAs started in 1993, when Lee et al. observed their involvement in the
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …

The molecular basis of herpes simplex virus latency

MP Nicoll, JT Proença… - FEMS microbiology …, 2012 - academic.oup.com
Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within
sensory neurones. Following primary infection, the virus replicates productively within …

Tinkering with translation: protein synthesis in virus-infected cells

D Walsh, MB Mathews, I Mohr - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Viruses are obligate intracellular parasites, and their replication requires host cell functions.
Although the size, composition, complexity, and functions encoded by their genomes are …

Coxsackievirus B3 replication and pathogenesis

FS Garmaroudi, D Marchant, R Hendry, H Luo… - Future …, 2015 - Taylor & Francis
Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites.
Indeed, they must cleverly exploit various compartments of host cells to complete their life …

The role of RNAi and microRNAs in animal virus replication and antiviral immunity

JL Umbach, BR Cullen - Genes & development, 2009 - genesdev.cshlp.org
The closely related microRNA (miRNA) and RNAi pathways have emerged as important
regulators of virus–host cell interactions. Although both pathways are relatively well …

The role of microRNAs in the pathogenesis of herpesvirus infection

D Piedade, JM Azevedo-Pereira - Viruses, 2016 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs important in gene regulation. They are
able to regulate mRNA translation through base-pair complementarity. Cellular miRNAs …