Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

Defects of articular cartilage present a unique clinical challenge due to its poor self-healing
capacity and avascular nature. Current surgical treatment options do not ensure consistent …

Tissue engineering (TE) has brought new hope for articular cartilage regeneration, as TE
can provide structural and functional substitutes for native tissues. The basic elements of TE …

Engineered bladder tissues, created with autologous bladder cells seeded on
biodegradable scaffolds, are being developed for use in patients who need cystoplasty …

Introduction The use of human umbilical cord Wharton Jelly-derived mesenchymal stem
cells (hWJ-MSCs) has been considered a new potential source for future safe applications in …

In the year 2000, Hanahan and Weinberg defined the six Hallmarks of Cancer as: self-
sufficiency in growth signals, evasion of apoptosis, insensitivity to antigrowth mechanisms …

Life expectancy has dramatically increased around the world over the last few decades, and
staying healthier longer, without chronic disease, has become an important issue. Although …

Background aims Subcutaneous fat represents a valuable reservoir of adipose-derived stem
cells (ASCs) in the stromal vascular fraction (SVF), widely exploited in regenerative …

Mesenchymal stem cells (MSCs), distributed in many tissues in the human body, are
multipotent cells capable of differentiating in specific directions. It is usually considered that …

Organ transplantation remains to be a treatment of choice for patients suffering from
irreversible organ failure. Immunosuppressive (IS) drugs employed to maintain the allograft …