Transforming growth factor-β signaling: from tissue fibrosis to therapeutic opportunities

LL Ren, XJ Li, TT Duan, ZH Li, JZ Yang… - Chemico-biological …, 2023 - Elsevier
Fibrosis refers to the excessive deposition of extracellular matrix components in the
processes of wound repair or tissue regeneration after tissue damage. Fibrosis occurs in …

The implications of FASN in immune cell biology and related diseases

Y Xiao, Y Yang, H Xiong, G Dong - Cell Death & Disease, 2024 - nature.com
Fatty acid metabolism, particularly fatty acid synthesis, is a very important cellular
physiological process in which nutrients are used for energy storage and biofilm synthesis …

Exploring the potential of treating chronic liver disease targeting the PI3K/Akt pathway and polarization mechanism of macrophages

Y Yang, X Jia, M Qu, X Yang, Y Fang, X Ying, M Zhang… - Heliyon, 2023 - cell.com
Chronic liver disease is a significant public health issue that can lead to considerable
morbidity and mortality, imposing an enormous burden on healthcare resources …

Artemether Attenuates Gut Barrier Dysfunction and Intestinal Flora Imbalance in High-Fat and High-Fructose Diet-Fed Mice

X Ren, J Xu, Y Xu, Q Wang, K Huang, X He - Nutrients, 2023 - mdpi.com
Intestinal inflammation is a key determinant of intestinal and systemic health, and when our
intestines are damaged, there is disruption of the intestinal barrier, which in turn induces a …

Comparative proteomic analysis of pathological characterization of adipose tissue remodeling induced by high-fat diet and high-carbohydrate diet in grass carp …

M Wei, X Yuan, L Song, H Li, H Ji, J Sun - Aquaculture, 2024 - Elsevier
Our previous research found that excessive accumulation of adipose tissue is an important
factor that reduces fish tolerance and utilization of high-energy feeds and limits the …

SIRT4 通过调控MAPK 信号通路和脂代谢途径抑制胰腺癌细胞增殖和侵袭及裸鼠移植瘤生长# br

刘俊, 陈海强, 刘世乾, 唐博 - 中国癌症防治杂志, 2023 - zgazfz.com
目的探讨SIRT4 调控MAPK 信号通路和脂代谢途径对胰腺癌细胞增殖和侵袭及裸鼠移植瘤生长
的影响. 方法收集2021 年6 月1 日—2022 年7 月28 日于广西医科大学第一附属医院肝胆外科经 …

Evaluation of the efficacy and safety of artemether emulsion on localized senile pruritus: A randomized pilot study

HQ He, WT Shen, Q Pei, JB Fei, Y Yu, HH Qin… - Medicine, 2022 - journals.lww.com
Background: Localized senile pruritus is a continued health problem for the elderly. This
study aimed to evaluate the efficacy and safety of artemether emulsion on localized senile …

[PDF][PDF] 콜라겐-유도의혈소판에서사이클릭뉴클레오티드의조절을통한Artemether 의항혈전효과

박창은, 이동하 - Journal of Applied Biological Chemistry, 2022 - e-sciencecentral.org
Although normal activation of platelets is important in the process of hemostasis, excessive
or abnormal activation of platelets can lead to cardiovascular diseases. Therefore, the …