Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets

G Basile, S Kahraman, E Dirice, H Pan, JM Dreyfuss… - Genome medicine, 2021 - Springer
Background Human pancreatic islets are a central focus of research in metabolic studies.
Transcriptomics is frequently used to interrogate alterations in cultured human islet cells …

Allele-specific regulatory effects on the pig transcriptome

Y Lin, J Li, L Chen, J Bai, J Zhang, Y Wang, P Liu… - …, 2023 - academic.oup.com
Background Allele-specific expression (ASE) refers to the preferential expression of one
allele over the other and contributes to adaptive phenotypic plasticity. Here, we used a …

Endomitosis controls tissue-specific gene expression during development

LM van Rijnberk, R Barrull-Mascaró… - PLoS …, 2022 - journals.plos.org
Polyploid cells contain more than 2 copies of the genome and are found in many plant and
animal tissues. Different types of polyploidy exist, in which the genome is confined to either 1 …

Single-nucleus RNA sequencing and lipidomics reveal characteristics of transcriptional and lipid composition in porcine longissimus dorsi muscle

L Yi, Q Li, J Zhu, W Cheng, Y Xie, Y Huang, H Zhao… - BMC genomics, 2024 - Springer
Background Global per capita meat consumption continues to rise, especially pork. Meat
quality is influenced by the content of intramuscular fat (IMF) as a key factor. The longissimus …

Single cell RNA-seq analysis of the flexor digitorum brevis mouse myofibers

RX Verma, S Kannan, BL Lin, KM Fomchenko… - Skeletal Muscle, 2021 - Springer
Background Skeletal muscle myofibers can be separated into functionally distinct cell types
that differ in gene and protein expression. Current single cell expression data is generally …