With an increasing interest in cocrystals due to various advantages, demand for large-scale
cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach …

Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …

Despite their widespread use for purification, our current methods for the development of
solution crystallization processes lack a sufficient understanding on how impurities …

Crystal engineering is an emerging tool for altering the physicochemical properties of drug
candidates. The objective of the current investigation was to develop cocrystals of …

Pharmaceutical cocrystals offer a promising strategy to increase the solubility and
dissolution rate of poorly soluble drugs. However, their manufacturing process requires a …

A solvent free process for the formation of carbamazepine (CBZ)–trans-cinnamic acid (TCA)
cocrystals, in stoichiometric ratios, was developed using continuous hot melt extrusion …

This study presents characterization and physicochemical properties of a new cocrystal of
ketoconazole (KTZ). Cocrystal formation of KTZ with two different coformers, ie nicotinamide …

Although cocrystals have undergone a recent boost in popularity, limited time is spent on
exploring the variety of possible cocrystal phases, which is likely due to the popularity and …

Crystallization can be regarded as a self-assembly process in which randomly organized
molecules in a fluid come together to form an ordered three-dimensional molecular array …

Solubility data are compiled and reviewed for 33 nonsteroidal anti-inflammatory drugs
dissolved in neat organic solvents and in well-defined binary and ternary organic solvents …