[HTML][HTML] The hidden potential of glycomarkers: Glycosylation studies in the service of cancer diagnosis and treatment

K Grzesik, M Janik, D Hoja-Łukowicz - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
Abstract Changes in the glycosylation process appear early in carcinogenesis and evolve
with the growth and spread of cancer. The correlation of the characteristic glycosylation …

Decoding the glycoproteome: a new frontier for biomarker discovery in cancer

K He, M Baniasad, H Kwon, T Caval, G Xu… - Journal of Hematology & …, 2024 - Springer
Cancer early detection and treatment response prediction continue to pose significant
challenges. Cancer liquid biopsies focusing on detecting circulating tumor cells (CTCs) and …

Comprehensive serum glycopeptide spectra analysis to identify early-stage epithelial ovarian cancer

M Mikami, K Tanabe, T Imanishi, M Ikeda, T Hirasawa… - Scientific reports, 2024 - nature.com
Epithelial ovarian cancer (EOC) is widely recognized as the most lethal gynecological
malignancy; however, its early-stage detection remains a considerable clinical challenge. To …

Comparative N-glycoproteomics analysis of clinical samples via different mass spectrometry dissociation methods

W Zeng, S Zheng, T Su, J Cheng, Y Mao… - Frontiers in …, 2022 - frontiersin.org
Site-specific N-glycosylation characterization requires intact N-glycopeptide analysis based
on suitable tandem mass spectrometry (MS/MS) method. Electron-transfer/higher-energy …

Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma

A Visconti, N Rossi, H Deriš, KA Lee, M Hanić… - Bmc cancer, 2023 - Springer
Abstract Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment
of melanoma and other cancers. However, no reliable biomarker of survival or response has …

Orosomucoid 2 upregulation mediates liver injury‐induced colorectal cancer liver metastasis by promoting EMT and cell migration

X Wei, L Wang, B Yang, Y Ma, W Yuan, J Ma - Cancer Science, 2025 - Wiley Online Library
The relationship between drug‐induced liver injury and liver metastasis of colorectal cancer
and the underlying mechanisms are not well understood. In this study, we used carbon …

Apprising diagnostic and prognostic biomarkers in cutaneous melanoma—Persistent updating

SR Georgescu, CI Mitran, MI Mitran, C Matei… - Journal of Personalized …, 2022 - mdpi.com
The incidence of melanoma, a very aggressive skin cancer, has increased over the past few
decades. Although there are well-established clinical, dermoscopic and histopathological …

The role of clinical glyco (proteo) mics in precision medicine

Y van der Burgt, M Wuhrer - Molecular & Cellular Proteomics, 2023 - ASBMB
Glycoproteomics reveals site-specific O-and N-glycosylation that may influence protein
properties including binding, activity, and half-life. The increasingly mature toolbox with …

Variability of human Alpha-1-acid glycoprotein N-glycome in a Caucasian population

F Vučković, M Novokmet, D Šoić, J Štambuk… - …, 2024 - academic.oup.com
Abstract Aim Alpha-1-acid glycoprotein (AGP) is a highly glycosylated protein in human
plasma and one of the most abundant acute phase proteins in humans. Glycosylation plays …

[PDF][PDF] COVID-19

P DU - mars, 2020 - initiative-communiste.fr
OPEX). Mais face au «durcissement» de l'État bourgeois (ce que nous appelons fascisation)
et à la marche aux guerres impérialistes, il faut que nous œuvrions de toutes nos forces pour …