Nanoparticle toxicology

W Yang, L Wang, EM Mettenbrink… - Annual Review of …, 2021 - annualreviews.org
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …

[HTML][HTML] Mechanisms of silver nanoparticle release, transformation and toxicity: a critical review of current knowledge and recommendations for future studies and …

B Reidy, A Haase, A Luch, KA Dawson, I Lynch - Materials, 2013 - mdpi.com
Nanosilver, due to its small particle size and enormous specific surface area, facilitates more
rapid dissolution of ions than the equivalent bulk material; potentially leading to increased …

Magnetite pollution nanoparticles in the human brain

BA Maher, IAM Ahmed… - Proceedings of the …, 2016 - National Acad Sciences
Biologically formed nanoparticles of the strongly magnetic mineral, magnetite, were first
detected in the human brain over 20 y ago [Kirschvink JL, Kobayashi-Kirschvink A …

Biological metals and metal-targeting compounds in major neurodegenerative diseases

KJ Barnham, AI Bush - Chemical Society Reviews, 2014 - pubs.rsc.org
Multiple abnormalities occur in the homeostasis of essential endogenous brain biometals in
age-related neurodegenerative disorders, Alzheimer's disease, Parkinson's disease …

Airborne, vehicle-derived Fe-bearing nanoparticles in the urban environment: a review

T Gonet, BA Maher - Environmental Science & Technology, 2019 - ACS Publications
Airborne particulate matter poses a serious threat to human health. Exposure to nanosized
(< 0.1 μm), vehicle-derived particulates may be hazardous due to their bioreactivity, their …

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Increased iron levels and decreased tissue integrity in hippocampus of Alzheimer's disease detected in vivo with magnetic resonance imaging

EP Raven, PH Lu, TA Tishler… - Journal of …, 2013 - content.iospress.com
Background: Iron can catalyze damaging free radical reactions. With age, iron accumulates
in brain gray matter regions and may contribute to the risk of developing age-related …

Biosynthesis of magnetic nanoparticles from nano-degradation products revealed in human stem cells

A Van de Walle, A Plan Sangnier… - Proceedings of the …, 2019 - National Acad Sciences
While magnetic nanoparticles offer exciting possibilities for stem cell imaging or tissue
bioengineering, their long-term intracellular fate remains to be fully documented. Besides, it …

[HTML][HTML] Iron status in the elderly

SJ Fairweather-Tait, AA Wawer, R Gillings… - Mechanisms of ageing …, 2014 - Elsevier
Iron deficiency anaemia is prevalent in older age, particularly after the age of 80. Serum
ferritin concentrations also decline, although there is no evidence to suggest that changes in …

Tumor microenvironment and nanotherapeutics: intruding the tumor fort

AVVVR Kiran, GK Kumari, PT Krishnamurthy… - Biomaterials …, 2021 - pubs.rsc.org
Over recent years, advancements in nanomedicine have allowed new approaches to
diagnose and treat tumors. Nano drug delivery systems exploit the enhanced permeability …