Neuroimaging of pain in animals allows us to better understand mechanisms of pain
processing and modulation. In this review, we discuss recently published brain imaging …

Pain is considered a multidimensional experience that embodies not merely sensation, but
also emotion and perception. As is appropriate for this complexity, pain is represented and …

With concurrent global epidemics of chronic pain and opioid use disorders, there is a critical
need to identify, target and manipulate specific cell populations expressing the mu-opioid …

Pain is a complex experience involving sensory, emotional, and cognitive aspects, and
multiple networks manage its processing in the brain. Examining how pain transforms into a …

Background and objective Cervical spondylosis (CS) is often accompanied by persistent
cervical pain, and psychological complications including depression and anxiety, which …

Assessing clinical pain and metrics related to function or quality of life predominantly relies
on patient reported subjective measures. These outcome measures are generally not …

The antineoplastic agent oxaliplatin is a first-line treatment for colorectal cancer. However,
neuropathic pain, characterized by hypersensitivity to cold, emerges soon after treatment. In …

Maintaining effective analgesia during invasive procedures performed under general
anesthesia is important for minimizing postoperative complications and ensuring satisfactory …

Purpose Functional magnetic resonance imaging (fMRI) visualizes hemodynamic responses
associated with brain and spinal cord activation. Various types of pain have been objectively …

Introduction: The complex and multidimensional nature of pain poses a major challenge in
clinical pain assessments. In this study, we aimed to evaluate a novel approach combining …