Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Immunotherapy is currently the most rapidly advancing area of clinical oncology, and
provides the unprecedented opportunity to effectively treat, and even cure, several …

Purpose: To construct an immune-related gene prognostic index (IRGPI) for head and neck
squamous cell carcinoma (HNSCC) and clarify the molecular and immune characteristics …

Macrophages have a leading position in the tumor microenvironment (TME) which paves the
way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites …

Promising targeted treatments and immunotherapy strategies in oncology and
advancements in our understanding of molecular pathways that underpin cancer …

Tumor-associated macrophages (TAMs) promote cancer cell proliferation, invasion, and
metastasis by producing various mediators. Although preclinical studies demonstrated that …

Tumor-associated macrophages (TAMs) are major component of leukocytic infiltrate of
tumors and play important roles in progression and regression of tumors. Tumor …

Identification of mutations in the gene encoding the serine/threonine-protein kinase, BRAF,
and constitutive activation of the mitogen-activated protein kinase (MAPK) pathway in …

IgE antibodies are key mediators of antiparasitic immune responses, but their potential for
cancer treatment via antibody-dependent cell-mediated cytotoxicity (ADCC) has been little …

Macrophages' role in the evolution of solid tumours is a well accepted fact, with the M1-like
macrophages having an anti-tumour role and the M2-like macrophages having a pro-tumour …