Since the beautiful images of Santiago Ramón y Cajal provided a first glimpse into the
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …

In the mature brain, functionally distinct areas connect to specific targets, mediating network
activity required for function. New insights are still occurring regarding how specific …

Layer 5 extratelencephalic (ET) neurons are present across neocortical areas and send
axons to multiple subcortical targets,,,,–. Two cardinal subtypes exist,:(1) Slco2a1 …

Translation modulates the timing and amplification of gene expression after transcription.
Brain development requires uniquely complex gene expression patterns, but large-scale …

During neocortex development, cortical projection neurons (PN) are sequentially produced
and assemble into circuits underlying our interactions with the environment. Cortical PN are …

Direct neuronal reprogramming is a promising approach to replace neurons lost due to
disease via the conversion of endogenous glia reacting to brain injury into neurons …

Developing mammalian brains are characterized by disproportionate growth of the forebrain
compared to other regions. How this localized expansion occurs is, however, largely …

The cerebral cortex consists of hierarchically organized areas interconnected by reciprocal
axonal projections. However, the coordination of neurogenesis to optimize neuronal …

The majority of neocortical projection neurons are generated indirectly from radial glial cells
(RGCs) mediated by intermediate progenitor cells (IPCs) in mice. IPCs are thought to be a …

Introduction: The gray short-tailed opossum, Monodelhis domestica (M. domestica), is a
widely used marsupial model species that presents unique advantages for …