Abstract Matrix metalloproteinase‐9 (MMP‐9) is a member of the metzincin family of mostly
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …

Spinal cord injury is currently incurable and treatment is limited to minimising secondary
complications and maximising residual function by rehabilitation. Improved understanding of …

Functional recovery following a spinal cord injury (SCI) is challenging. Traditional drug
therapies focus on the suppression of immune responses; however, strategies for alleviating …

The cystic cavity that develops following injuries to brain or spinal cord is a major obstacle
for tissue repair in central nervous system (CNS). Here we report that injection of imidazole …

The aim of this paper is to give an overview of acute complications of spinal cord injury
(SCI). Along with motor and sensory deficits, instabilities of the cardiovascular …

Perineuronal nets (PNN) are extracellular matrix (ECM) assemblies that preferentially
ensheath parvalbumin (PV) expressing interneurons. Converging evidence indicates that …

Throughout the body, the extracellular matrix (ECM) provides structure and organization to
tissues and also helps regulate cell migration and intercellular communication. In the injured …

Glial scarring following severe tissue damage and inflammation after spinal cord injury (SCI)
is due to an extreme, uncontrolled form of reactive astrogliosis that typically occurs around …

One of the more important recent advances in neuroscience research is the understanding
that there is extensive communication between the immune system and the central nervous …

Nonhealing chronic wounds are major complications of diabetes resulting in> 70,000
annual lower-limb amputations in the United States alone. The reasons the diabetic wound …