Peptide-based vaccines: current progress and future challenges

RJ Malonis, JR Lai, O Vergnolle - Chemical reviews, 2019 - ACS Publications
Vaccines have had a profound impact on the management and prevention of infectious
disease. In addition, the development of vaccines against chronic diseases has attracted …

A comprehensive review on cancer vaccines and vaccine strategies in hepatocellular carcinoma

A Tojjari, A Saeed, M Singh, L Cavalcante, IH Sahin… - Vaccines, 2023 - mdpi.com
HCC, the most prevalent form of primary liver cancer, presents a substantial global health
challenge due to its high mortality and limited therapeutic options. This review delves into …

Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target

RCO Sanches, S Tiwari, LCG Ferreira… - Frontiers in …, 2021 - frontiersin.org
Schistosomiasis remains a serious health issue nowadays for an estimated one billion
people in 79 countries around the world. Great efforts have been made to identify good …

Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii

V Solanki, V Tiwari - Scientific reports, 2018 - nature.com
The emergence of drug-resistant Acinetobacter baumannii is the global health problem
associated with high mortality and morbidity. Therefore it is high time to find a suitable …

Design of a multi-epitope-based vaccine targeting M-protein of SARS-CoV2: an immunoinformatics approach

VS Ayyagari, V TC, AP K, K Srirama - Journal of biomolecular …, 2022 - Taylor & Francis
In the present study, one of the targets present on the envelopes of coronaviruses,
membrane glycoprotein (M) was chosen for the design of a multi-epitope vaccine by …

In Silico Prediction of a Multitope Vaccine against Moraxella catarrhalis: Reverse Vaccinology and Immunoinformatics

MA Soltan, N Elbassiouny, H Gamal, EB Elkaeed… - Vaccines, 2021 - mdpi.com
Moraxella catarrhalis (M. catarrhalis) is a Gram-negative bacterium that can cause serious
respiratory tract infections and middle ear infections in children and adults. M. catarrhalis …

Vaccine design from the ensemble of surface glycoprotein epitopes of SARS-CoV-2: an immunoinformatics approach

N Rahman, F Ali, Z Basharat, M Shehroz, MK Khan… - Vaccines, 2020 - mdpi.com
The present study aimed to work out a peptide-based multi-epitope vaccine against the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We predicted different B …

Reverse vaccinology approach to design a novel multi-epitope subunit vaccine against avian influenza A (H7N9) virus

M Hasan, PP Ghosh, KF Azim, S Mukta, RA Abir… - Microbial …, 2019 - Elsevier
H7N9, a novel strain of avian origin influenza was the first recorded incidence where a
human was transited by a N9 type influenza virus. Effective vaccination against influenza A …

Multi-epitope vaccine for monkeypox using pan-genome and reverse vaccinology approaches

RG Swetha, S Basu, S Ramaiah, A Anbarasu - Viruses, 2022 - mdpi.com
Outbreaks of monkeypox virus infections have imposed major health concerns worldwide,
with high morbidity threats to children and immunocompromised adults. Although …

Exploring the cancer-testis antigen BORIS to design a novel multi-epitope vaccine against breast cancer based on immunoinformatics approaches

E Mahdevar, A Safavi, A Abiri, A Kefayat… - Journal of …, 2022 - Taylor & Francis
Recently, cancer immunotherapy has gained lots of attention to replace the current
chemoradiation approaches and multi-epitope cancer vaccines are manifesting as the next …