IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Maternal serum cytokine concentrations in healthy pregnancy and preeclampsia

T Spence, PJ Allsopp, AJ Yeates… - Journal of …, 2021 - Wiley Online Library
The maternal immune response is essential for successful pregnancy, promoting immune
tolerance to the fetus while maintaining innate and adaptive immunity. Uncontrolled …

[HTML][HTML] Severe preeclampsia goes along with a cytokine network disturbance towards a systemic inflammatory state

MB Pinheiro, OA Martins-Filho, APL Mota, PN Alpoim… - Cytokine, 2013 - Elsevier
Although preeclampsia causes high maternal/fetal morbidity and mortality, the etiology of
this multi-system disorder still remains to be elucidated. Herein, we have characterized the …

Evidence-based revised view of the pathophysiology of preeclampsia

A Ahmed, H Rezai, S Broadway-Stringer - Hypertension: from basic …, 2017 - Springer
Preeclampsia is a life-threatening vascular disorder of pregnancy due to a failing stressed
placenta. Millions of women risk death to give birth each year and globally each year, almost …

Altered endothelial nitric oxide signaling as a paradigm for maternal vascular maladaptation in preeclampsia

G Osol, NL Ko, M Mandalà - Current hypertension reports, 2017 - Springer
Abstract Purpose of Review The goal of this review is to present the newest insights into
what we view as a central failure of cardiovascular adaptation in preeclampsia (PE) by …

[PDF][PDF] Evaluation of levels of some inflammatory cytokines in preeclamptic women in owerri

OR Emeka-Obi, NC Ibeh, EI Obeagu… - Journal of …, 2021 - academia.edu
Preeclampsia is a serious and life-threatening pregnancy complication. In this study, the
levels of inflammatory cytokines were measured in preeclamptic women in Owerri, Imo …

The role of cytokines as inflammatory mediators in preeclampsia

I Udenze, C Amadi, N Awolola, CC Makwe - Pan African Medical Journal, 2015 - ajol.info
Research Page 1 Page number not for citation purposes 1 The role of cytokines as
inflammatory mediators in preeclampsia Ifeoma Udenze1,&, Casimir Amadi2, Nicholas …

Placental proinflammatory state and maternal endothelial dysfunction in preeclampsia

J Valencia-Ortega, A Zárate, R Saucedo… - Gynecologic and …, 2019 - karger.com
Objective: To evaluate the placental and decidual gene expression and maternal and
umbilical serum concentrations of tumor necrosis factor alpha, interleukin 6 (IL-6), IL-8, IL …

The frequency of acute atherosis in normal pregnancy and preterm labor, preeclampsia, small-for-gestational age, fetal death and midtrimester spontaneous abortion

YM Kim, P Chaemsaithong, R Romero… - The Journal of …, 2015 - Taylor & Francis
Objective: Acute atherosis is characterized by subendothelial lipid-filled foam cells, fibrinoid
necrosis and perivascular lymphocytic infiltration. This lesion is generally confined to non …

Unravelling the theories of pre‐eclampsia: are the protective pathways the new paradigm?

A Ahmed, W Ramma - British journal of pharmacology, 2015 - Wiley Online Library
Pre‐eclampsia is a vascular disorder of pregnancy where anti‐angiogenic factors, systemic
inflammation and oxidative stress predominate, but none can claim to cause pre‐eclampsia …