The plasma membrane of eukaryotic cells is not a simple sheet of lipids and proteins but is
differentiated into subdomains with crucial functions. Caveolae, small pits in the plasma …

Our understanding of endocytosis has evolved remarkably in little more than a decade. This
is the result not only of advances in our knowledge of its molecular and biological workings …

Lipid rafts are plasma membrane microdomains enriched in cholesterol and sphingolipids
that are involved in the lateral compartmentalization of molecules at the cell surface …

Abstract Caveolin-1 (Cav1) is a multifunctional scaffolding protein with multiple binding
partners that is associated with cell surface caveolae and the regulation of lipid raft domains …

• Introduction• Raft‐dependent endocytosis encompasses various pathways• Cav1 and the
regulation of raft‐dependent endocytosis• Signaling and raft‐dependent endocytosis• …

Caveolins (Cavs) are integrated plasma membrane proteins that are complex signaling
regulators with numerous partners and whose activity is highly dependent on cellular …

Abstract ErbB receptors (EGFR (ErbB1), ErbB2, ErbB3, and ErbB4) are important regulators
of normal growth and differentiation, and they are involved in the pathogenesis of cancer …

The plasma membrane (PM) is subjected to multiple mechanical forces, and it must adapt
and respond to them. PM invaginations named caveolae, with a specific protein and lipid …

Caveolin 1 (Cav1) is a required structural component of caveolae, and its phosphorylation
by Src is associated with an increase in caveolae-mediated endocytosis. Here we …

• Introduction• The caveolins• Caveolin‐1 in cell physiology‐Caveolin‐1 distribution‐
Caveolin‐1 and internalization‐Caveolin‐1 and cholesterol‐Regulation of caveolin‐1 …