Leptin as a key regulator of the adipose organ

C Picó, M Palou, CA Pomar, AM Rodríguez… - Reviews in Endocrine …, 2022 - Springer
Leptin is a hormone primarily produced by the adipose tissue in proportion to the size of fat
stores, with a primary function in the control of lipid reserves. Besides adipose tissue, leptin …

Impact of early nutrition, physical activity and sleep on the fetal programming of disease in the pregnancy: a narrative review

J Moreno-Fernandez, JJ Ochoa, M Lopez-Frias… - Nutrients, 2020 - mdpi.com
Early programming is the adaptation process by which nutrition and environmental factors
alter development pathways during prenatal growth, inducing changes in postnatal …

[HTML][HTML] Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring

M Dahlhoff, S Pfister, A Blutke, J Rozman… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Vulnerability of the fetus upon maternal obesity can potentially occur during all
developmental phases. We aimed at elaborating longer-term health outcomes of fetal …

Metabolic programming of obesity by energy restriction during the perinatal period: different outcomes depending on gender and period, type and severity of restriction

C Picó, M Palou, T Priego, J Sánchez… - Frontiers in physiology, 2012 - frontiersin.org
Epidemiological studies in humans and controlled intervention studies in animals have
shown that nutritional programming in early periods of life is a phenomenon that affects …

[PDF][PDF] Good maternal nutrition: the best start in life

World Health Organization - 2016 - apps.who.int
This publication presents a summary of the most recent evidence on maternal nutrition, the
prevention of obesity and noncommunicable disease. It provides an overview and explores …

Obese mothers supplemented with melatonin during gestation and lactation ameliorate the male offspring's pancreatic islet cellular composition and beta-cell function

BA Nagagata, M Ajackson, F Ornellas… - … Origins of Health and …, 2023 - cambridge.org
Melatonin supplementation to obese mothers during gestation and lactation might benefit
the pancreatic islet cellular composition and beta-cell function in male offspring adulthood …

Characterisation of the maternal response to chronic phase shifts during gestation in the rat: implications for fetal metabolic programming

TJ Varcoe, MJ Boden, A Voultsios, MD Salkeld… - PLoS …, 2013 - journals.plos.org
Disrupting maternal circadian rhythms through exposure to chronic phase shifts of the
photoperiod has lifelong consequences for the metabolic homeostasis of the fetus, such that …

Maternal dietary fat affects milk fatty acid profile and impacts on weight gain and thermogenic capacity of suckling rats

T Priego, J Sánchez, AP García, A Palou, C Picó - Lipids, 2013 - Springer
We aimed to assess the effects of maternal supplementation with the main fat sources used
in the human Western diet (olive oil, butter, margarine) on milk FA composition and on …

Strategies for reversing the effects of metabolic disorders induced as a consequence of developmental programming

MH Vickers, DM Sloboda - Frontiers in physiology, 2012 - frontiersin.org
Obesity and the metabolic syndrome have reached epidemic proportions worldwide with far-
reaching health care and economic implications. The rapid increase in the prevalence of …

Maternal consumption of a cafeteria diet during lactation in rats leads the offspring to a thin-outside-fat-inside phenotype

CA Pomar, R Van Nes, J Sánchez, C Picó… - International Journal of …, 2017 - nature.com
Methods: Nursing rats were fed a control diet or a cafeteria diet during lactation. Milk was
obtained at different time points of lactation. Offspring (males and females) were weaned …