Pathogenesis of gram-negative bacteremia

CL Holmes, MT Anderson, HLT Mobley… - Clinical microbiology …, 2021 - Am Soc Microbiol
Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

“Omics” Technologies - What Have They Told Us About Uropathogenic Escherichia coli Fitness and Virulence During Urinary Tract Infection?

S Torres-Puig, V García, K Stærk… - Frontiers in cellular …, 2022 - frontiersin.org
Uropathogenic Escherichia coli (UPEC) is the main etiological agent of urinary tract infection
(UTI), a widespread infectious disease of great impact on human health. This is further …

Rapid Growth of Uropathogenic Escherichia coli during Human Urinary Tract Infection

VS Forsyth, CE Armbruster, SN Smith, A Pirani… - MBio, 2018 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) strains cause most uncomplicated urinary tract
infections (UTIs). These strains are a subgroup of extraintestinal pathogenic E. coli (ExPEC) …

[HTML][HTML] Genome-wide analysis of fitness factors in uropathogenic Escherichia coli in a pig urinary tract infection model

V García, K Stærk, MSA Alobaidallah… - Microbiological …, 2022 - Elsevier
Uropathogenic Escherichia coli (UPEC) is the primary cause of urinary tract infections (UTIs)
in animals and humans. We applied Transposon-Directed Insertion Site sequencing …

Nitrate Metabolism Modulates Biosynthesis of Biofilm Components in Uropathogenic Escherichia coli and Acts as a Fitness Factor During Experimental Urinary Tract …

AJ Martín-Rodríguez, M Rhen, K Melican… - Frontiers in …, 2020 - frontiersin.org
To successfully colonize a variety of environments, bacteria can coordinate complex
collective behaviors such as biofilm formation. To thrive in oxygen limited niches, bacteria's …

A cynomolgus monkey E. coli urinary tract infection model confirms efficacy of new FimH vaccine candidates

L Chorro, T Ciolino, CL Torres, A Illenberger… - Infection and …, 2024 - journals.asm.org
The increase in urinary tract infections (UTI) caused by antibiotic-resistant Escherichia coli
requires the development of new therapeutic agents and prophylactic vaccines. To evaluate …

A discovery down under: decoding the draft genome sequence of Pantoea stewartii from Australia's Critically Endangered western ground parrot/kyloring (Pezoporus …

RT White, W Taylor, N Klukowski… - Microbial …, 2023 - microbiologyresearch.org
Pantoea stewartii, a plant pathogen, is primarily transmitted through contaminated seeds
and insect vectors, with the corn flea beetle (Chaetocnema pulicaria) being the primary …

Adaptation of arginine synthesis among uropathogenic branches of the Escherichia coli phylogeny reveals adjustment to the urinary tract habitat

ME Hibbing, KW Dodson, V Kalas, SL Chen… - MBio, 2020 - Am Soc Microbiol
Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli
(UPEC). UPEC pathogenesis requires passage through a severe population bottleneck …

Epididymitis: ascending infection restricted by segmental boundaries

A Stammler, T Hau, S Bhushan, A Meinhardt… - Human …, 2015 - academic.oup.com
STUDY QUESTION Is the regionalization of epididymitis related to epididymal
segmentation? SUMMARY ANSWER We show for the first time that luminal ascent of …

A Thermosensitive, Phase-Variable Epigenetic Switch: pap Revisited

M Zamora, CA Ziegler, PL Freddolino… - … and Molecular Biology …, 2020 - Am Soc Microbiol
It has been more than a decade since the last comprehensive review of the phase-variable
uropathogen-associated pyelonephritis-associated pilus (pap) genetic switch. Since then …