Central to eukaryotic cell function, transport into and out of the nucleus is largely mediated
by members of the Importin (IMP) superfamily of transporters of α-and β-types. The first …

Background and Objectives: It is generally accepted that inflammatory cells found in the
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …

Simple Summary Prostate cancer is a serious health problem for men around the world, and
it is often caused by inflammation in the prostate gland. The authors of this article explore …

Goniothalamin (GTN) is an isolated compound from several plants of the genus
Goniothalamus, and its anticancer effect against several cancers was reported. However …

Introduction: Aged-related brain damage and gut microbiome disruption are common.
Research affirms that modulating the microbiota-gut-brain axis can help reduce age-related …

Background Brazilian berry is a fruit popularly known as “Jaboticaba,” rich in bioactive
compounds with antioxidant and anti‐inflammatory properties. Senescence and overweight …

This review covers the chemistry and biological aspects of goniothalamin-related styryl
lactones isolated from natural sources. This family of secondary metabolites has been …

Prostate cancer is the second most diagnosed cancer in the world, and alternative methods
to prevent and treat different lesion grades need to be evaluated. The objective was to …

Background Benign prostatic hyperplasia (BPH) is a condition generally associated with
advanced age in men that can be accompanied by bothersome lower urinary tract symptoms …

Aging and overweight are involved in prostatic lesion development, due to their association
with cell proliferation, hormonal imbalance and angiogenesis. The jaboticaba fruit is rich in …