Regenerative medicine is a new and promising mode of therapy for patients who have
limited or no other options for the treatment of their illness. Due to their pleotropic therapeutic …

There is a growing interest in cell therapies using mesenchymal stromal cells (MSCs) for
repairing bone defects. MSCs have the ability to differentiate into osteoprogenitors and …

Traditional Chinese medicine (TCM) has demonstrated superior therapeutic effect for
musculoskeletal diseases for thousands of years. Recently, the herbal extracts of TCM have …

Extracellular vesicles are known as actual intermediaries of intercellular communications,
such as biological signals and cargo transfer between different cells. A variety of cells …

ECM components include a number of osteoinductive and osteoconductive factors, which
are involved in bone fracture healing. In this study, a combination of adipose derived …

Background Topography at different scales plays an important role in directing
mesenchymal stem cell differentiation including adipose-derived stem cells (ASCs) and the …

Abstract Background Mesenchymal Stem Cells (MSCs) therapy has become a new coming
focus of clinical research in regenerative medicine. However, only a small number of …

Mesenchymal stem cells (MSCs) are recognized as an attractive tool owing to their self-
renewal and differentiation capacity, and their ability to secrete bioactive molecules and to …

Objective (s): The scarcity of articular cartilage defect to repair due to absence of blood
vessels and tissue engineering is one of the promising approaches for cartilage …

Purpose Although bone marrow mesenchymal stem cells (BMMSCs) have been reported to
exhibit a protective effect on animal models of chronic kidney disease (CKD), the exact …