This Review explores the dynamic behavior of water within nanopores and biological
channels in lipid bilayer membranes. We focus on molecular simulation studies, alongside …

To generate the desired effect in the human body, the active pharmaceutical ingredient
usually needs to interact with a receptor located on the cell membrane or inside the cell …

Chemotherapy has been validated unavailable for treatment of renal cell carcinoma (RCC)
in clinic due to its intrinsic drug resistance. Sensitization of chemo‐drug response plays a …

Artificial channels made of carbon nanotube (CNT) porins are promising candidates for
applications in filtration and molecular delivery devices. Their symmetric shape and high …

Macrophage recognition and phagocytosis of crystals is critical for the associated fibrosis
and cancer. Of note, multi-walled carbon nanotubes (MWCNTs), the highly representative …

Chemistry is in a powerful position to synthetically replicate biomolecular structures. Adding
functional complexity is key to increase the biomimetics' value for science and technology …

Self-assembling cyclic peptide nanotubes can form nanopores when they are inserted in
lipid bilayers, acting as ion and/or water permeable channels. In order to improve the …

Heterogeneities (eg, membrane proteins and lipid domains) and deformations (eg, highly
curved membrane regions) in biological lipid membranes cause lipid packing defects that …

We use coarse-grain molecular simulations to investigate the structural and dynamics
differences between an asymmetric and a symmetrical membrane, both containing beta …

As a newly emerging two-dimensional material, black phosphorus (BP) has received broad
attention in the field of biomedical applications. Prior to its clinical application, its cytotoxicity …