Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement

V Aggarwal, HS Tuli, M Tania, S Srivastava… - Seminars in cancer …, 2022 - Elsevier
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …

Organization, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions

P Kanchanawong, DA Calderwood - Nature Reviews Molecular Cell …, 2023 - nature.com
The ability of animal cells to sense, adhere to and remodel their local extracellular matrix
(ECM) is central to control of cell shape, mechanical responsiveness, motility and signalling …

[图书][B] Wintrobe's clinical hematology

MM Wintrobe - 2009 - books.google.com
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Actin remodeling defects leading to autoinflammation and immune dysregulation

R Papa, F Penco, S Volpi, M Gattorno - Frontiers in Immunology, 2021 - frontiersin.org
A growing number of monogenic immune-mediated diseases have been related to genes
involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate …

Baicalein: A metabolite with promising antineoplastic activity

HS Tuli, V Aggarwal, J Kaur, D Aggarwal, G Parashar… - Life Sciences, 2020 - Elsevier
Cancer, being a multifactorial disease has diverse presentation in different subgroups which
is mainly attributed to heterogenous presentation of tumor cells. This cancer cell …

Turning universal O into rare Bombay type blood

I Anso, A Naegeli, JO Cifuente, A Orrantia… - Nature …, 2023 - nature.com
Red blood cell antigens play critical roles in blood transfusion since donor incompatibilities
can be lethal. Recipients with the rare total deficiency in H antigen, the Oh Bombay …

Garcinol exhibits anti-neoplastic effects by targeting diverse oncogenic factors in tumor cells

V Aggarwal, HS Tuli, J Kaur, D Aggarwal, G Parashar… - Biomedicines, 2020 - mdpi.com
Garcinol, a polyisoprenylated benzophenone, is the medicinal component obtained from
fruits and leaves of Garcinia indica (G. indica) and has traditionally been extensively used …

Structural and functional diversity of neutrophil glycosylation in innate immunity and related disorders

J Ugonotti, S Chatterjee… - Molecular aspects of …, 2021 - Elsevier
The granulated neutrophils are abundant innate immune cells that utilize bioactive
glycoproteins packed in cytosolic granules to fight pathogenic infections, but the neutrophil …

Selectin-mediated signaling—Shedding light on the regulation of integrin activity in neutrophils

A Cappenberg, M Kardell, A Zarbock - Cells, 2022 - mdpi.com
As a consequence of tissue injury or infection, neutrophils are recruited in a stepwise
recruitment process from the bloodstream into the surrounding tissue. Selectins are a family …

Hematologically important mutations: leukocyte adhesion deficiency (second update)

D Roos, K Van Leeuwen, M Madkaikar… - Blood Cells, Molecules …, 2023 - Elsevier
Leukocyte adhesion deficiency (LAD) is an immunodeficiency caused by defects in the
adhesion of leukocytes (especially neutrophils) to the blood vessel wall. As a result, patients …