Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies

HR Hofer, RS Tuan - Stem cell research & therapy, 2016 - Springer
Adult mesenchymal stem cells (MSCs) represent a subject of intense experimental and
biomedical interest. Recently, trophic activities of MSCs have become the topic of a number …

Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling

KH Griffin, SW Fok, J Kent Leach - NPJ Regenerative Medicine, 2022 - nature.com
Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to
address defects arising from trauma, inefficient wound repair, or congenital malformation …

Stem cell injections in knee osteoarthritis: a systematic review of the literature

HI Pas, M Winters, HJ Haisma, MJJ Koenis… - British journal of sports …, 2017 - bjsm.bmj.com
Objective Stem cell injection for knee osteoarthritis (KOA) is an emerging new therapy, and
we aimed to review its evidence of efficacy. Design Systematic review. Eligibility criteria …

Clinical efficacy and safety of mesenchymal stem cell transplantation for osteoarthritis treatment: a meta-analysis

M Yubo, L Yanyan, L Li, S Tao, L Bo, C Lin - PloS one, 2017 - journals.plos.org
Purpose The aim of this study was to evaluate the therapeutic efficacy and safety of
mesenchymal stem cells (MSCs) for the treatment of patients with knee osteoarthritis (OA) …

Procedural treatments for knee osteoarthritis: a review of current injectable therapies

LM Billesberger, KM Fisher, YJ Qadri… - Pain Research and …, 2020 - Wiley Online Library
Knee osteoarthritis is a common painful degenerative condition affecting the aging
Canadian population. In addition to pain and disability, osteoarthritis is associated with …

Human mesenchymal stem cells genetically engineered to overexpress brain-derived neurotrophic factor improve outcomes in Huntington's disease mouse models

K Pollock, H Dahlenburg, H Nelson, KD Fink, W Cary… - Molecular Therapy, 2016 - cell.com
Huntington's disease (HD) is a fatal degenerative autosomal dominant neuropsychiatric
disease that causes neuronal death and is characterized by progressive striatal and then …

Comparative matched-pair analysis of the injection versus implantation of mesenchymal stem cells for knee osteoarthritis

YS Kim, OR Kwon, YJ Choi, DS Suh… - … American journal of …, 2015 - journals.sagepub.com
Background: The mesenchymal stem cell (MSC)–based tissue engineering approach has
been developed to address the problem of articular cartilage repair in knee osteoarthritis …

Therapeutic approaches in the management of knee osteoarthritis

B Uivaraseanu, CM Vesa, DM Tit… - Experimental and …, 2022 - spandidos-publications.com
Osteoarthritis (OA) is a common, frequently met degenerative disease, that generates pain
and decreasing functionality; risk of suffering from this disorder increases with ageing. Being …

Non-operative management of osteoarthritis of the knee joint

R Vaishya, GB Pariyo, AK Agarwal, V Vijay - Journal of clinical orthopaedics …, 2016 - Elsevier
Osteoarthritis is a chronic disorder of synovial joints in which there is progressive softening
and disintegration of articular cartilage accompanied by the growth of osteophytes …

Therapeutic potential of differentiated mesenchymal stem cells for treatment of osteoarthritis

O Ham, CY Lee, R Kim, J Lee, S Oh, MY Lee… - International journal of …, 2015 - mdpi.com
Osteoarthritis (OA) is a chronic, progressive, and irreversible degenerative joint disease.
Conventional OA treatments often result in complications such as pain and limited activity …