Parkinson disease (PD) is a neurodegenerative disorder characterized by motor and non-
motor symptoms which relentlessly and progressively lead to substantial disability and …

Growing evidence supports dopamine's role in aversive states, yet systematic reviews
focusing on dopamine receptors in defensive behaviors are lacking. This study presents a …

D2/3 receptor agonists are effective treatments for Parkinson's disease (PD), but can
precipitate impulse control disorders (ICD s) including gambling disorder (GD). The …

The dorsal striatum has been linked to decision-making under conflict, but the mechanism
by which striatal neurons contribute to approach-avoidance conflicts remains unclear. We …

Prenatal stress (PNS) has its negative impact on both the infant hippocampal neurogenesis
and pregnancy outcomes in the neonates that serves as a risk factor for postnatal …

Fibromyalgia is a disease characterized by lowered pain threshold, mood disorders, and
decreased muscular strength. It results from a complex dysfunction of the nervous system …

Pain is the major non-motor symptom in Parkinson's disease (PD). Preclinical studies have
mostly investigated mechanical pain by considering the decrease in a nociceptive threshold …

Background: A possible genetic contribution of dopamine D3 receptor (DRD3) to cognitive
impairment in Parkinson's disease (PD) has yet to be investigated. Objective: To explore the …

Introduction Dopamine agonists have been widely used to treat patients with Parkinson's
disease, but concerns related to their well-known side effects might prevent their use even …

The central nucleus of the amygdala (CeA) is involved in the expression of fear and has
been implicated in several anxiety disorders. This structure is densely innervated by DAergic …