To date, the combination of histological sectioning, staining, and microscopic assessment of
the 2D sections is still the golden standard for structural and compositional analysis of …

Imaging in clinical trials is used to evaluate subject eligibility, and/or efficacy of intervention,
supporting decision making in drug development by ascertaining treatment effects on joint …

Large bone defects cannot form a callus and exhibit high complication rates even with the
best treatment strategies available. Tissue engineering approaches often use scaffolds …

Dr. McIlwraith's Joint Disease in the Horse, 2nd Edition is the only book to give you a full
account of equine joint disease, combining a thorough, up-to-date survey of scientific …

Biological tissues have a complex and heterogeneous 3D structure, which is only partially
revealed by standard histomorphometry in 2D. We here present a novel chemical compound …

A novel class of near‐infrared fluorescent contrast agents was developed. These agents
target cartilage with high specificity and this property is inherent to the chemical structure of …

Bioreactors have the potential to advance the clinical application of cell-based therapies.
Cell expansion bioreactors have been used commercially for therapeutic applications; …

X-ray computed tomography (CT) is the most commonly used imaging technique for
noninvasive diagnosis of disease. In order to improve tissue specificity and prevent adverse …

Objective Mouse articular cartilage (AC) is mostly assessed by histopathology and its
mechanics is poorly characterised. In this study:(1) we developed non-destructive imaging …

Cartilage tissue exhibits early degenerative changes with onset of osteoarthritis (OA). Early
diagnosis is critical as there is only a narrow time window during which therapeutic …