Programmed cell death (PCD) is fundamentally important for plant development, abiotic
stress responses and immunity, but our understanding of its regulation remains fragmented …

Caspases are restricted to animals, while other organisms, including plants, possess
metacaspases (MCAs), a more ancient and broader class of structurally related yet …

Programmed cell death (PCD) is a regulatory process essential for the development and
maintenance of multicellular integrity. While the objectives and execution of PCD are …

Metacaspases are cysteine proteases present in plants, fungi and protists. While the
association of metacaspases with cell death is studied in a range of organisms, their native …

The importance of metacaspases in programmed cell death and tissue differentiation is
known, but their significance in disease stress response, particularly in a crop plant …

This thesis encompasses two projects aimed at combating vector-borne infectious diseases.
The first project focuses on developing public health insecticides against diseases …