Compositions of matter for detection assays

A Ganguli, A Mostafa, J Berger, A Pandey… - US Patent …, 2023 - Google Patents
The present disclosure describes compositions of matter comprising a ribonucleoprotein
complex comprising a nucleic acid-guided nuclease and a guide RNA, and further …

Compositions of matter for detection assays

A Ganguli, A Mostafa, J Berger, A Pandey… - US Patent …, 2023 - Google Patents
The present disclosure describes compositions of matter comprising a ribonucleoprotein
complex comprising a nucleic acid-guided nuclease and a guide RNA, and further …

Tuning cascade assay kinetics via molecular design

A Ganguli, A Mostafa, J Berger, A Pandey - US Patent 11,859,182, 2024 - Google Patents
The present disclosure relates to compositions of matter and assay methods used to detect
one or more target nucleic acids of interest in a sample. The compositions and methods …

Tuning cascade assay kinetics via molecular design

A Ganguli, A Mostafa, J Berger, A Pandey - US Patent 11,820,983, 2023 - Google Patents
The present disclosure relates to compositions of matter and assay methods used to detect
one or more target nucleic acids of interest in a sample. The compositions and methods …

Signal boost cascade assay

A Ganguli, A Pandey, A Mostafa, J Berger - US Patent 12,129,468, 2024 - Google Patents
The present disclosure relates to compositions of matter and assay methods used to detect
one or more target nucleic acids of interest in a sample. The compositions and methods …

Sample splitting for multiplexed detection of nucleic acids without amplification

P Belgrader - US Patent 12,060,602, 2024 - Google Patents
The present disclosure relates to multiplex assay methods used to detect target nucleic
acids of interest from several to many sources in a sample without amplification of the target …

Detection of nucleic acid and non-nucleic acid target molecules

S Murali, A Garst, A Ganguli, K Sawant… - US Patent …, 2024 - Google Patents
US12091707B2 - Detection of nucleic acid and non-nucleic acid target molecules - Google
Patents US12091707B2 - Detection of nucleic acid and non-nucleic acid target molecules …

Detection of nucleic acid and non-nucleic acid target molecules

S Murali, A Ganguli, K Sawant… - US Patent 11,965,205, 2024 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …

Compositions of matter for detection assays

A Ganguli, A Mostafa, J Berger, A Pandey - US Patent 11,987,839, 2024 - Google Patents
The present disclosure describes compositions of matter comprising a ribonucleoprotein
complex comprising a nucleic acid-guided nuclease and a guide RNA, and further …

CRISPR-based programmable RNA editing

BA Wiedenheft, JE Nichols, AA Nemudraia… - US Patent …, 2024 - Google Patents
CRISPR RNA-guided nucleases are routinely used for sequence-specific manipulation of
DNA. While CRISPR-based DNA editing has become routine, analogous methods for …