Kaempferol: antimicrobial properties, sources, clinical, and traditional applications

A Periferakis, K Periferakis, IA Badarau… - International journal of …, 2022 - mdpi.com
Flavonoids are a category of plant-derived compounds which exhibit a large number of
health-related effects. One of the most well-known and studied flavonoids is kaempferol …

Isolation and characterization of novel hydroxyflavone from Kigelia africana (Lam.) Benth. fruit ethyl acetate fraction against CHO 1 and HeLa cancer cell lines: In vitro …

AD Ogunlakin, MA Sonibare, OE Yeye… - Journal of Molecular …, 2023 - Elsevier
This study is aimed at evaluating the anti-proliferative activity of a novel hydroxyflavone
isolated for the first time from Kigelia africana fruit, against cervical cancer (HeLa) and …

Flavonoids from Brazilian Cerrado: biosynthesis, chemical and biological profile

JC Peixoto, BJ Neves, FG Vasconcelos, HB Napolitano… - Molecules, 2019 - mdpi.com
Flavonoids are highly bioactive compounds with very low toxicity, which makes them
attractive starting points in drug discovery. This study aims to provide information on plant …

Quality performances of sweet pepper under farming management

G Caruso, VV Stoleru, NC Munteanu… - Notulae Botanicae …, 2019 - notulaebotanicae.ro
Conventional management of sweet pepper is based on farming practices characterized by
the use of chemicals with harmful environmental impact. In order to investigate innovative …

Carvacrol promotes cell cycle arrest and apoptosis through PI3K/AKT signaling pathway in MCF-7 breast cancer cells

A Mari, G Mani, SN Nagabhishek, G Balaraman… - Chinese journal of …, 2021 - Springer
Objective To examine the role of carvacrol in modulating PI3K/AKT signaling involved in
human breast cancer pathogenesis using in vitro experimental model MCF-7 cells. Methods …

Morphine decreases cytotoxicity and mutagenicity of doxorubicin in vitro: Implications for cancer chemotherapy

JT de Sousa, RR Dihl, FBM Boaretto… - Chemico-Biological …, 2023 - Elsevier
Morphine is the most common opioid analgesic administered to treat pain in patients
undergoing cancer chemotherapy. This study aimed to evaluate the cytotoxic and mutagenic …

Antioxidative, Antiproliferative and Antimicrobial Activities of Phenolic Compounds from Three Myrcia Species

C Dos Santos, RS Galaverna, CFF Angolini… - Molecules, 2018 - mdpi.com
Myrcia bella Cambess., Myrcia fallax (Rich.) DC. and Myrcia guianensis (Aubl.)
DC.(Myrtaceae) are trees found in Brazilian Cerrado. They have been widely used in folk …

Characterization of the in vitro cytotoxic effects of brachydins isolated from Fridericia platyphylla in a prostate cancer cell line

HL Nunes, K Tuttis, JM Serpeloni… - Journal of Toxicology …, 2020 - Taylor & Francis
ABSTRACT Brachydins (Br) A, B, and C are flavonoids extracted from Fridericia platyphylla
(Cham.) LG Lohmann roots (synonym Arrabidaea brachypoda), whose extract previously …

LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds

AFL Specian, JM Serpeloni, K Tuttis, DL Ribeiro… - Cytotechnology, 2016 - Springer
Brazilian flora biodiversity has been widely investigated to identify effective and safe
phytotherapeutic compounds. Among the investigated plant species, the Byrsonima genus …

The Chemical Profile of Senna velutina Leaves and Their Antioxidant and Cytotoxic Effects

JF Campos, DTH de Castro, MJ Damião… - Oxidative Medicine …, 2016 - Wiley Online Library
Natural products can be a source of biomolecules with antioxidant activity which are able to
prevent oxidative stress‐induced diseases and show antitumor activity, making them …