Advanced brain imaging for the diagnosis of Alzheimer disease

YTT Wang, P Rosa-Neto, S Gauthier - Current opinion in …, 2023 - journals.lww.com
Brain imaging techniques using PET improve our understanding of the different AD-related
pathologies and their relationship with each other along the course of disease. With more …

Multisite comparison of MRI defacing software across multiple cohorts

AE Theyers, M Zamyadi, M O'Reilly, R Bartha… - Frontiers in …, 2021 - frontiersin.org
With improvements to both scan quality and facial recognition software, there is an
increased risk of participants being identified by a 3D render of their structural neuroimaging …

Small and large magnetic resonance imaging–visible perivascular spaces in the basal ganglia of parkinson's disease patients

J Ramirez, SA Berberian, DP Breen, F Gao… - Movement …, 2022 - Wiley Online Library
Background Although previously thought to be asymptomatic, recent studies have
suggested that magnetic resonance imaging–visible perivascular spaces (PVS) in the basal …

Olfactory dysfunction predicts disease progression in Parkinson's disease: a longitudinal study

R He, Y Zhao, Y He, Y Zhou, J Yang, X Zhou… - Frontiers in …, 2020 - frontiersin.org
Background and Objective: Olfactory dysfunction (hyposmia) is an important non-motor
symptom of Parkinson's disease (PD). To investigate the potential prognostic value of …

CAPTURE ALS: the comprehensive analysis platform to understand, remedy and eliminate ALS

V Picher-Martel, C Magnussen, M Blais… - … Lateral Sclerosis and …, 2023 - Taylor & Francis
The absence of disease modifying treatments for amyotrophic lateral sclerosis (ALS) is in
large part a consequence of its complexity and heterogeneity. Deep clinical and biological …

Characteristics of the Ontario neurodegenerative disease research initiative cohort

KM Sunderland, D Beaton, SR Arnott… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Understanding synergies between neurodegenerative and cerebrovascular
pathologies that modify dementia presentation represents an important knowledge gap …

White matter hyperintensity burden predicts cognitive but not motor decline in Parkinson's disease: results from the Ontario Neurodegenerative Diseases Research …

DC Carvalho de Abreu… - European Journal of …, 2023 - Wiley Online Library
Background and purpose The pathophysiology of Parkinson's disease (PD) negatively
affects brain network connectivity, and in the presence of brain white matter hyperintensities …

Perivascular spaces mediate a relationship between diabetes and other cerebral small vessel disease markers in cerebrovascular and neurodegenerative diseases

J Zebarth, R Kamal, G Perlman, M Ouk… - Journal of Stroke and …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) and hypertension are risk factors for cerebral small vessel
disease (SVD); however, few studies have characterised their relationships with MRI-visible …

Soluble epoxide hydrolase derived linoleic acid oxylipins, small vessel disease markers, and neurodegeneration in stroke

D Yu, N Liang, J Zebarth, Q Shen… - Journal of the …, 2023 - Am Heart Assoc
Background Cerebral small vessel disease is associated with higher ratios of soluble‐
epoxide hydrolase derived linoleic acid diols (12, 13‐dihydroxyoctadecenoic acid [DiHOME] …

[HTML][HTML] Exploring biomarkers of processing speed and executive function: The role of the anterior thalamic radiations

J Ferris, B Greeley, NM Yeganeh, S Rinat, J Ramirez… - NeuroImage: Clinical, 2022 - Elsevier
Introduction Processing speed and executive function are often impaired after stroke and in
typical aging. However, there are no reliable neurological markers of these cognitive …