Quinoxalines, also known as benzo [a] pyrazines, constitute an important class of nitrogen- containing heterocyclic compounds as a result of their widespread prevalence in natural …
Heterocycles of synthetic and natural origin are a well-established class of compounds representing a broad range of organic molecules that constitute over 60% of drugs and …
OO Ajani - European journal of medicinal chemistry, 2014 - Elsevier
Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide biological properties and diverse therapeutic applications in medicinal research. They are …
GK Rathod, M Jain, KK Sharma, S Das, A Basak… - European journal of …, 2022 - Elsevier
Malaria remains a major vector borne disease claiming millions of lives worldwide due to infections caused by Plasmodium sp. Discovery and development of antimalarial drugs have …
E Vicente, S Pérez-Silanes, LM Lima, S Ancizu… - Bioorganic & medicinal …, 2009 - Elsevier
New series of 3-phenylquinoxaline 1, 4-di-N-oxide with selective activity against Mycobacterium tuberculosis have been prepared and evaluated. Thirty-four of the seventy …
GI Buravchenko, AE Shchekotikhin - Pharmaceuticals, 2023 - mdpi.com
N-Oxides of heterocyclic compounds are the focus of medical chemistry due to their diverse biological properties. The high reactivity and tendency to undergo various rearrangements …
C Upadhyay, M Chaudhary… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction The unique physicochemical properties and chemical diversity of organofluorine compounds have remarkably contributed for their wide utility in the area of …
VA Mamedov, NA Zhukova - Progress in heterocyclic chemistry, 2013 - Elsevier
In the second part of this two-part review (for Part 1 see VA Mamedov, A. Nataliya, NA Zhukova, Prog. Heterocycl. Chem. 2012, 24, 55), recent advances in the synthesis of …
J Jampilek - Current medicinal chemistry, 2014 - ingentaconnect.com
Antimicrobial diazanaphthalenes are indispensable in the treatment of various infections. The quinoxaline scaffold possesses unique physicochemical properties and provides a …