Lipopolysaccharide delivery systems in innate immunity

J Liu, R Kang, D Tang - Trends in Immunology, 2024 - cell.com
Lipopolysaccharide (LPS), a key component of the outer membrane in Gram-negative
bacteria (GNB), is widely recognized for its crucial role in mammalian innate immunity and …

The dangerous liaisons in innate immunity involving recombinant proteins and endotoxins: Examples from the literature and the Leptospira field

D Bonhomme, JM Cavaillon, C Werts - Journal of Biological Chemistry, 2024 - ASBMB
Endotoxins, also known as lipopolysaccharides (LPS), are essential components of cell
walls of diderm bacteria such as Escherichia coli. LPS are microbe-associated molecular …

A Surface-Enhanced Raman Spectroscopy-Based Biosensor for the Detection of Biological Macromolecules: The Case of the Lipopolysaccharide Endotoxin …

G Rusciano, A Capaccio, A Sasso, A Capo… - International Journal of …, 2023 - mdpi.com
The development of sensitive methods for the detection of endotoxin molecules, such as
lipopolysaccharides (LPS), is essential for food safety and health control. Conventional …

Generation of Endotoxin-Specific Monoclonal Antibodies by Phage and Yeast Display for Capturing Endotoxin

AC Fux, C Casonato Melo, L Schlahsa… - International Journal of …, 2024 - mdpi.com
Endotoxin, a synonym for lipopolysaccharide (LPS), is anchored in the outer membranes of
Gram-negative bacteria. Even minute amounts of LPS entering the circulatory system can …

Recovering What Matters: High Protein Recovery after Endotoxin Removal from LPS-Contaminated Formulations Using Novel Anti-Lipid A Antibody Microparticle …

C Casonato Melo, AC Fux, M Himly, NG Bastús… - International Journal of …, 2023 - mdpi.com
Endotoxins or lipopolysaccharides (LPS), found in the outer membrane of Gram-negative
bacterial cell walls, can stimulate the human innate immune system, leading to life …

The multifaceted role of c-di-AMP signaling in the regulation of Porphyromonas gingivalis lipopolysaccharide structure and function

S Ghods, A Muszyński, H Yang, RS Seelan… - Frontiers in Cellular …, 2024 - frontiersin.org
Background This study unveils the intricate functional association between cyclic di-3', 5'-
adenylic acid (c-di-AMP) signaling, cellular bioenergetics, and the regulation of …

The interaction between oral microbiota and gut microbiota in atherosclerosis

X Li, Q Li, L Wang, H Ding, Y Wang, Y Liu… - Frontiers in …, 2024 - frontiersin.org
Atherosclerosis (AS) is a complex disease caused by multiple pathological factors
threatening human health-the pathogenesis is yet to be fully elucidated. In recent years …

Dental Stem Cells and Lipopolysaccharides: A Concise Review

BA Rodas-Junco, SE Hernández-Solís… - International Journal of …, 2024 - mdpi.com
Dental tissue stem cells (DTSCs) are well known for their multipotent capacity and
regenerative potential. They also play an important role in the immune response of …

[HTML][HTML] Supramolecular assembly of micellar aggregates is the basis of low endotoxin recovery (LER) in a drug formulation that can be resolved by a whole blood …

AB Schromm, W Correa, N Gisch, F Steiniger… - Biomedicine & …, 2024 - Elsevier
Lipopolysaccharide (LPS, endotoxin) is ubiquitous and represents a harmful contaminant of
pharmaceutical compounds, recombinant biologicals and drug products. The pyrogen can …

Hospital Acquired Sepsis, Disease Prevalence, and Recent Advances in Sepsis Mitigation

M Garvey - Pathogens, 2024 - mdpi.com
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection, commonly associated with nosocomial transmission. Gram-negative bacterial …