Abstract Background Tea (Camellia sinensis) has a rich history and is widely consumed
across many countries, and is categorized into green tea, white tea, oolong tea, yellow tea …

Many health problems including chronic diseases are closely associated with oxidative
stress and inflammation. Tea has abundant phenolic compounds with various health …

The regulatory significance of ubiquitin-specific peptidase 32 (USP32) in tumor is significant,
nevertheless, the biological roles and regulatory mechanisms of USP32 in non-small cell …

Ubiquitination is a crucial type of protein modification which helps to control substrate
degradation and maintain cell homeostasis. Recent studies suggest that ubiquitination and …

Ferroptosis holds great potential as a therapeutic approach for gastric cancer (GC), a
prevalent and deadly malignant tumor associated with high rates of incidence and mortality …

Ubiquitination of proliferating cell nuclear antigen (PCNA) triggers pathways of DNA
damage tolerance, including mutagenic translesion DNA synthesis, and comprises a …

VEXAS syndrome is a new disease entity with symptoms that can mimic hematological,
rheumatic and dermatological diseases. It is important to take a multidisciplinary approach to …

Background Ubiquitination and ubiquitin-like protein post-translational modifications play an
enormous number of roles in cellular processes. These modifications are constituted of …

The green tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) and some of its analogs
potently inhibit the ubiquitin-activating enzyme Uba1. In an effort to understand the possible …

The discovery of UBA6 in 2007 has challenged the ubiquitin field, as for a long time, the
ubiquitin-activating enzyme 1 (UBA1) was thought to be the sole E1 responsible for the …